中国儿童单纯性肥胖与出生体重关系的Meta分析  

Correlation between birth weight and children'simple obesity in China:a meta-analysis

作　　者：王熙蓓 杨文亮[1,2] 田德红[1] 王玉[1] 于国伟[3] 

机构地区：[1]兰州大学公共卫生学院,甘肃兰州730000 [2]兰州大学循证医学中心,甘肃兰州730000 [3]西北民族大学西部环境与健康研究所,甘肃兰州730000

出　　处：《中国儿童保健杂志》2015年第10期1077-1080,共4页Chinese Journal of Child Health Care

基　　金：国家科技惠民计划资助(2012GS620101)

摘　　要：目的系统评价我国儿童单纯性肥胖与出生体重的相关性,为控制和预防儿童单纯性肥胖提供理论依据。方法计算机检索PubMed、EMbase、Web of science、CNKI、CBM、VIP和WanFang Data,收集关于中国儿童单纯性肥胖与出生体重关系的病例-对照研究,检索时限2000年1月-2014年11月。采用RevMan5.1软件进行Meta分析。结果最终纳入18个研究,共17 442例研究对象。Meta分析结果显示:与正常体重组相比,高出生体重儿童发生单纯性肥胖的危险性较高,差异有统计学意义[OR=2.09,95%CI:1.90~2.30,P<0.000 01];儿童单纯性肥胖在低出生体重方面差异无统计学意义[OR=0.92,95%CI:0.41~2.06,P=0.84]。结论高出生体重是儿童单纯性肥胖的危险因素;低出生体重与儿童单纯性肥胖无关联。Objective To systematically review the correlation between simple obesity and birth weight in children,and provide a theoretical basis for the control and prevention children＂ simple obesity. Methods Case-control study about the correlation between Chinese childreffs simple obesity and birth weight were collected in PubMed, EMbase, Web of science, CNKI, CBM, VIP and Wan^ang Data, which were published from January 2000 to November 2014. Meta-analysis was conducted by using RevMan 5.1 software. Results Finally 18 studies including 17 442 participants were included. The results of meta-analysis showed that high birth weight children had a higher risk of simple obesity with a significant difference compared with the normal weight group（OR=2.09,95 %CI 1.90～2.30,P《0. 000 01）. In addition,it showed that no significant differences were found be- tween childreffs simple obesity and low birth weight （OR=0. 92,95%CI..0. 41～2.06,P=0. 84）. Conclusion High birth weight is a risk factor of simple obesity, while no correlation exists between low birth weight and simple obesity in children.

关 键 词：出生体重 单纯性肥胖 儿童 META分析 病例-对照研究 

分 类 号：R179[医药卫生—妇幼卫生保健]