速力菲联合阿胶治疗妇产科缺铁性贫血的疗效分析  

Analysis on effect of ferrous succinate combined with donkey-hide gelatin for treatment of iron deficiency anemia in department of gynaecology and obstetrics

作　　者：张文琴[1] 

机构地区：[1]江苏省南京市江宁医院妇产科,211100

出　　处：《检验医学与临床》2015年第19期2931-2932,共2页Laboratory Medicine and Clinic

摘　　要：目的探讨速力菲联合阿胶治疗妇产科缺铁性贫血(IDA)的临床应用效果。方法选择妇产科IDA患者共127例作为研究对象,随机分为两组,对照组(n=62)采用硫酸亚铁和维生素C片进行常规治疗,观察组(n=65)采用速力菲联合阿胶进行治疗。观察并分析两组患者治疗后的血红蛋白(Hb)、红细胞比容(Hct)、血清铁蛋白(SF)及血清转铁蛋白饱和度(TSAT)指标的变化情况,比较两种治疗方法下的临床总有效率和不良反应率差异。结果治疗后,两组患者的Hb、Hct、SF、TSAT指标均明显提高,并以观察组的上升幅度更高。观察组的临床治疗总有效率高达95.38%(62/65),不良反应率低至7.69%(5/65),均显著优于对照组的82.26%(51/62)、25.81%(16/62),两组间差异均有统计学意义(P<0.05)。结论速力菲联合阿胶应用于治疗妇产科IDA的临床疗效显著,安全性高,其效果显著优于常规治疗,值得在临床上推广使用。Objective To explore the clinical application effect of ferrous succinate combined with donkey‐hide gelatin for the treatment of iron deficiency anemia（IDA） in the department of gynecology and obstetrics .Methods 127 patients with IDA in the department of gynaecology and obstetrics of our hospital were selected as the research subjects and randomly divided into two groups .The control group（n= 62） were treated with the routine therapy of Ferrous Sulfate Tablets and Vitamin C Tablets ,while the observation group（n = 65）adopted the therapy of ferrous succinate combined with donkey‐hide gelatin .The changes of hemoglobin（Hb） ,hematocrit（Hct） ,serum ferritin（SF） and serum transferrin saturation（TSAT ） were observed and analyzed in the two groups .The differences of total ef‐fective rate and occurrence rate of adverse reaction were compared between the two kinds of treatment method .Re‐sults After treatment ,the indexes such as Hb ,Hct ,SF and TSAT in the two groups were significantly improved , but the elevation amplitude in the observation group was more higher .The total effective rate in the observation group was up to 95 .38% （62/65） and the adverse reaction rate was low to 7 .69% （5/65） ,which were significantly better than 82 .26% （51/62） and 25 .81% （16/62） in the control group ,the differences between the two groups were statistically significant（P〈 0 .05） .Conclusion Ferrous succinate combined with donkey‐hide gelatin has significant effect with high safety in the treatment of IDA in the department of obstetrics and gynecology ,its effect is significant‐ly superior to the conventional therapy ,which is worthy of being promoted and applied in clinic .

关 键 词：速力菲 阿胶 硫酸亚铁 有效率 不良反应 

分 类 号：R541.4[医药卫生—心血管疾病]