封闭式负压引流治疗老年腹部创伤及感染创面的临床疗效及安全性评价  

Clinical efficacy and safety of closed negative pressure drainage in treatment of elderly patients with abdominal trauma and wound infection

作　　者：陈道英[1] 彭宗银[2] 

机构地区：[1]四川省医学科学院四川省人民医院城东病区创伤外科,成都610110 [2]四川省医学科学院四川省人民医院城东病区重症监护室,成都610110

出　　处：《中国临床药理学杂志》2015年第19期1898-1900,共3页The Chinese Journal of Clinical Pharmacology

基　　金：四川省卫生厅科研基金资助项目(120081)

摘　　要：目的评价封闭式负压引流治疗老年腹部创伤及感染创面的临床疗效和安全性。方法将42例老年腹部创伤及感染创面患者随机分为试验组21例和对照组21例。对照组予以红霉素软膏每日涂抹2次和常规换药处理;试验组予以封闭式负压引流治疗,并配合抗菌治疗。用视觉模拟评分量表(VAS)比较治疗前后疼痛情况,用生活质量评分量表(QOL)比较治疗前后生活质量。比较2组患者的日引流量、换药次数、住院天数、1,2,3周的感染控制情况和不良反应情况。结果治疗后,试验组VAS评分(4.9±1.8)分低于对照组(6.5±2.2)分(P<0.05)。治疗后,试验组QOL评分(95.1±3.9)分高于对照组(82.8±10.7)分(P<0.01)。试验组日引流量(51.93±10.14)m L高于对照组(13.91±5.22)m L(P<0.01)。试验组换药次数(9.08±2.72)次、住院天数(20.56±4.95)d均少于对照组换药次数(18.07±5.54)次、住院天数(30.91±7.80)d(P<0.01)。试验组感染控制率95.21%优于对照组66.74%(P<0.05)。试验组不良反应发生率为0显著低于对照组23.80%(P<0.01)。结论封闭式负压引流在老年腹部创伤及感染创面的治疗中能有效地缓解患者的疼痛,加快创面愈合,有效控制感染,促进预后,改善患者的生活质量。Objective To investigate the curative effect of closed negative pressure drainage in treatment of elderly patients with abdominal trauma and wound infection. Methods Fourty- two cases of elderly patients with abdominal trauma and wound infection were randomly divided into control group（ n = 21） and treatment group（ n = 21）. Control group was given erythromycin ointment twice a day and conventional dressing treatment. Treatment group was taken the treatment of closed negative pressure drainage and antibacterial therapy. The pain situation as well as the life quality score before and after treatment by visual analogue rating scale（ VAS） was compared. Besides,the daily drainage,dressing,days of hospitalization,infection control situation 1,2,3 weeks and adverse drug reactions between the two groups were compared. Results After treatment,the VAS score（ 4. 9 ± 1. 8） points of treatment group was significantly lower than that of the control group with VAS score（ 6. 5 ± 2. 2）（ P〈0. 05）. The drainage（ 51. 93 ± 10. 14） m L of treatment group was higher than that of the control group（ P〈0. 01）.The bandage times（ 9. 08 ＋ 2. 72） and hospital stay（ 20. 56 ＋ 4. 95） d of treatment group were less than those of the control group with dressing change times（ 18. 07 ＋ 5. 54） and hospital stay（ 30. 91 ＋ 7. 80） d（ P〈0. 01）. infection control rate of treatment group（ 95. 21%） was higher that of control group（ 66. 74%）（ P〈0. 05）. After treatment,the life quality of treatment group（ 95. 1 ＋ 3. 9） is higher than that of control group（ 82. 8 ＋ 10. 7）,with significant difference（ P〈0. 01）. The incidences of adverse reactions in treatment group was 0,the control group was 23. 80%（ 5 /21）,difference between groups was statistically significant（ P〈0. 05）. Conclusion The closed negative pressure drainage has a high application value in the treatment of senile abdominal trauma and infection in the wound,which can ease the pain,accelera

关 键 词：腹部创伤 感染创面 封闭式负压引流 疼痛 生活质量 

分 类 号：R681.2[医药卫生—骨科学] R969.4[医药卫生—外科学]