硒催化硼氢化钠还原芳香族硝基化合物制备芳胺  

Selenium-catalyzed Reduction of Aromatic Nitro Compounds to Anilines with Sodium Borohydride

作　　者：蔡可迎[1] 赵学娇[1] 姚从兴 王丽[1] 

机构地区：[1]徐州工程学院化学化工学院,江苏徐州221018

出　　处：《化学世界》2015年第2期91-93,97,共4页Chemical World

摘　　要：以硒粉为催化剂、硼氢化钠为还原剂在温和条件下还原芳香族硝基化合物制备芳胺。以10mmol硝基苯为底物考察了溶剂、反应温度、硼氢化钠及硒粉用量等对苯胺收率的影响。适宜的反应条件如下：溶剂为乙醇-水（V（乙醇）∶V（水）=3∶1）,反应温度为50℃,硒粉用量为0.1g,硼氢化钠用量为12 mmol。在此条件下,10种芳香族硝基化合物被还原为相应芳胺的收率为11.2%~99.1%,底物中另一取代基的位置和性质对芳胺收率有较大影响。Under mild conditions,aromatic nitro compounds were reduced to anilines with sodium borohydride in the presence of selenium catalyst.The influences of solvent,reaction temperature and the amount of sodium borohydride were investigated with 10 mmol nitrobenzene as substrate.The suitable reaction conditions were as follows：ethanol and water（V（ethanol）∶V（water）= 3∶1）as solvent,reaction temperature 50℃,0.1g selenium and 12 mmol sodium borohydride.Under these conditions,ten aromatic nitro compounds were reduced to corresponding anilines with 11.2% ~99.1% yields.The position and property of the other substituent of the substrate exerted great influence on the yield.

关 键 词：硼氢化钠 还原 芳香族硝基化合物 硒 芳胺 

分 类 号：TQ246.3[化学工程—有机化工]