适宜复温速率对重型颅脑损伤亚低温治疗患者的效果研究  

The effects of appropriate rate of rewarming on treatment outcome during mild hypothermia therapy in patients with severe traumatic brain injury

作　　者：杨莘[1] 李冬[2] 刘芳[2] 王军[3] 吴瑛[4] 苏林霞 

机构地区：[1]首都医科大学宣武医院护理部,北京市100053 [2]首都医科大学宣武医院神经内科ICU,北京市100053 [3]首都医科大学宣武医院神经外科ICU,北京市100053 [4]首都医科大学护理学院,北京市100053

出　　处：《护理管理杂志》2015年第9期647-649,共3页Journal of Nursing Administration

基　　金：2012年度首都中医药及护理学研究专项课题(12ZYH11)

摘　　要：目的探讨重型颅脑损伤患者亚低温治疗过程中适宜的复温速率对其治疗效果的影响。方法将31例亚低温治疗的重型颅脑损伤患者随机分为3组，复温速率分别控制为〈0．05％／h、0．05-0．09％／h和0．10～0．25℃／h。收集复温过程中患者生命体征、颅内压变化、格拉斯哥评分及并发症等资料进行评定。结果患者复温达36．5℃时，复温速率〉O．10％／h组患者的颅内压值明显高于其他两组（P〈0．05）；3组患者格拉斯哥评分、生命体征及检验结果、并发症的差异无统计学意义（P〉0．05）。结论重型颅脑损伤患者亚低温治疗复温速率应控制于0．10℃／h以下。Objective To explore the effects of appropriate rate of rewarming on treatment outcome during mild hypothermia therapy in patients with severe traumatic brain injury. Methods Thirty - one cases of severe traumatic brain injury were randomly divided into 3 groups with rewarming rate of 〈 0.05 ℃/h, 0.05 -0.09 ℃/h and 0.10 - 0.25 ℃/h, respectively. Vital sighs,intracranial pressure, Glasgow Coma Scale （GCS）and complication of patients were measured during rewarming therapy. Results Intracranial pressure of patients in the group with rewarming rate of 0.10 - 0.25 ℃/h was significantly higher than the other two groups at rewarming temperature of 36.5 ℃ （P 〈 0.05）. Survival rates, vital signs, GCS and complications of patients were not different significantly in 3 groups（ P 〉 0.05 ）. Conclusion The rate of rewarming should be controlled below 0.10 ℃/h during mild hypothermia therapy in patients with severe trau- matic brain injury.

关 键 词：重型颅脑损伤 亚低温治疗 复温速率 

分 类 号：R473.6[医药卫生—护理学]