母代产前环境暴露对子代呼吸道变应性疾病的影响  

Prenatal environmental exposures influencing respiratory allergic diseases of offspring

作　　者：谭路[1] 许昱[1] 

机构地区：[1]武汉大学人民医院耳鼻咽喉头颈外科,武汉430060

出　　处：《临床耳鼻咽喉头颈外科杂志》2015年第20期1839-1842,共4页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

基　　金：国家自然科学基金(No:81371070);湖北省自然科学基金(No:2014CKB495)

摘　　要：变应性鼻炎（AR）、哮喘等呼吸道变应性疾病是儿童的好发疾病,其发病率呈上升趋势。1996-2003年,全球37个国家的66个地区中,有44个地区6~7岁儿童AR发病率明显上升;2009年武汉地区3~6岁儿童AR患病率达10.8%。Summary There is an accumulating number of evidence pointing to maternal influence on the origin of allergic diseases. Prenatal window represents a critical period in which the mother influence allergic diseases of offspring. Variable factors such as the specises, exposure time and exposure dose of maternal environmental exposures may be the critical factors that influence the morbidity of respiratory allergic diseases of offspring. In this review we summarize findings from recent studies in this field.

关 键 词：呼吸超敏反应 产前暴露迟发效应 子代 

分 类 号：R714.253[医药卫生—妇产科学]