PCT及CRP在新生儿坏死性小肠结肠炎的早期诊断价值  

Diagnostic Value of Procalcitonin Combined with C-Reactive Protein in Early Necrotizing Enterocolitis

作　　者：张爱梅[1] 孙志群[1] 邱晓梅[1] 尹延娥[1] 林新宇[1] 张立明[1] 

机构地区：[1]潍坊市人民医院新生儿科,山东潍坊261041

出　　处：《潍坊医学院学报》2015年第4期289-291,共3页Acta Academiae Medicinae Weifang

摘　　要：目的探讨降钙素原(PCT)、C反应蛋白(CRP)联合检测在新生儿坏死性小肠结肠炎(NEC)中的早期诊断价值。方法选取31例确诊为NEC的患儿,同期50例非感染早产儿作为对照,均进行PCT,CRP检测并进行分析。结果两组患儿PCT,CRP血清浓度之间比较,差异均有统计学意义(P<0.05),而且随病情进展,二者改变更为明显。结论 PCT,CRP联合检测有利于新生儿NEC的早期诊断,提高了诊断的准确率。Objective To investigate the diagnostic value of the procalcitonin （ PCT） combined with C-reac-tive protein（CRP）in early necrotizing enterocolitis （ NEC）.Methods Thirty-one patients with necrotizing enterocolitis were collected for the study group .Fifty patients without infection were selected as control group .Serum PCT,CRP levels from these infants were collected and analyzed at 0,24h.Results The positive rate of serum PCT and CRP levels was significantly higher in study group（P〈0.05） and the difference had statistical significance （P〈0.05）.Conclusion PCT and CRP detection not only contributes to the early diagnosis of neonatal NEC but also improve the diagnostic accu -racy.

关 键 词：降钙素原 C-反应蛋白 坏死性小肠结肠炎 婴儿 早产 

分 类 号：R725.7[医药卫生—儿科]