38例幼年型类风湿病临床分型与免疫学研究  

Clinical classification and immunology research of 38 cases of juvenile rheumatoid arthritis

作　　者：林言华 

机构地区：[1]广东省佛山市顺德区第一人民医院血液风湿科,528300

出　　处：《齐齐哈尔医学院学报》2015年第25期3757-3759,共3页Journal of Qiqihar Medical University

摘　　要：目的探讨幼年型类风湿性关节炎临床分型以及免疫学特点。方法回顾性分析我院2013年1月至2014年1月儿科收治的幼年型类风湿性关节炎(JRA)患儿38例为研究组,同时选取30健康幼儿为对照组,对研究组患儿的临床表现以及检查结果等加以分析。结果 38例患儿临床分型方面,全身型22例,多关节型11例,少关节型5例,研究组患儿的T淋巴细胞亚群和IL-2同对照组研究对象相比存在显著不同,差异有统计学意义(P<0.05)。结论 JRA的分型诊断主要通过临床特征,同时排除患儿的其他系统疾病,并应用其他辅助检查了解该病的活动性,同时在JRA的治疗方面应当长期规范治疗,从而避免影响患儿的预后。Objective To investigate the clinical classification of juvenile rheumatoid arthritis and immunological characteristics. Methods A retrospective analysis was done on the datas of 38 casesof pediatric juvenile rheumatoid arthritis（ JRA） admitted toour hospital during January 2013 and January 2014,and 30 healthy children were selected as the control group,the clinical manifestations and detection findings of children were analyzed. Results Among the 38 cases of children,22 cases of systemic type,11 cases of polyarticular type,and 5 cases of oligoarticular type. Differences of T lymphocyte subsets and IL- 2 between the two group was statistically significant（ P〈0. 05）. Conclusions The diagnosis of JRAtype primarily by clinical features and excluding other diseases in children and applying other supplementary examination to understand the disease activity,the treatment for JRA should be long- term therapy and specification,avoiding influence the prognosis of children.

关 键 词：3幼年型类风湿病 临床分型 免疫学 结缔组织疾病 风湿关节炎 

分 类 号：R711.71[医药卫生—妇产科学]