细辛医药相关中国发明专利分析  

Profiling on Invention Patents of Xi-Xin in China

作　　者：丹阳[1] 马运运 孙志一 刘海波[1,2] 

机构地区：[1]中国医学科学院北京协和医学院药用植物研究所,北京100193 [2]国家中医药管理局传统药物专利信息资源重点研究室,北京100080 [3]北京东方灵盾科技有限公司,北京100080

出　　处：《世界科学技术-中医药现代化》2015年第7期1355-1360,共6页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：北京市科委"首都市民健康项目培育"项目(Z131100006813045):生物药物专利信息服务系统研发;负责人:孙瑞阳

摘　　要：细辛是一种常用中药材,主要药用部位为根和根茎,自古便被列为上品,有诸多药用功效,中国药典规定品种为北细辛、汉城细辛和华细辛。对细辛相关发明专利进行分析,有助于了解其发明专利申请现状及发展趋势,进而推进该药物的产品研发和产业化发展,促进科技成果转化。本文使用《孔明专利信息搜索平台》进行专利检索,并利用Python、R语言等工具对检索结果进行收集、筛选、整理、统计、挖掘和分析,深入剖析国内的细辛相关医药发明专利申请的现状与发展趋势,为细辛的开发提供参考。细辛的发明专利申请热度逐年提高;细辛相关发明专利申请主要来自于中、韩、日、俄、美等国家和地区,涉及的主要临床应用为感冒、咳喘、头痛、风湿痹痛、抗菌消炎、心血管系统等疾病;细辛多与活血祛瘀药、解表药和补虚类药配伍。Xi-Xin, a commonly used traditional Chinese herbal medicine, was regarded as one of the top grade materia medica since ancient time. The main medical parts were the root and stem. TheChinese Pharmacopeiaregulated the types ofAsarum heterotropoidesvar. mandshuricum,A. sieboldiivar. seoulense, andA. sieboldii. Analysis onXi-Xin related invention and patent information was an important aspect to understand the patent application condition and development tendency. It will also promote the research, development and industrialization of this medicine and promote its scientific result transformation. The Kongfz Patent Search Engine was used in the patent searching. Python and R languages were used in the collection, screening, classification, statistics, digging and analysis. In-depth analysis was made on the domesticXi-Xin related medical invention, patent application condition and development tendency. It provided references for the development ofXi-Xin. The results showed that an ever-increasing number of patents onXi-Xin were＆amp;nbsp;available. TheXi-Xin related inventions and patent applications were mainly from China, Republic of Korea, Japan, Russia, the U.S.A., etc. The main clinical applications were common cold, cough, headache, rheumatism and arthralgia, antibiosis, antiphlogosis, and cardiovascular diseases.Xi-Xin was mostly combined with herbal medicine with the effects of invigorating blood circulation and removing blood stasis, relieving exterior syndrome, and tonifying deficiency.

关 键 词：北细辛 华细辛 汉城细辛 马兜铃科 中药专利 中药信息学 

分 类 号：R932[医药卫生—生药学] G255.53[医药卫生—药学]