经皮冠状动脉介入治疗后冠心病心绞痛患者生存质量影响因素的分析  

Influencing factors on quality of life after percutaneous coronary intervention in patients with angina pectoris

作　　者：姚远[1] 梁峰[2] 沈珠军[3] 

机构地区：[1]北京市平谷区医院医疗保健部,北京101200 [2]首都医科大学大兴医院心内科 [3]北京协和医院心内科

出　　处：《中国介入心脏病学杂志》2015年第9期508-511,共4页Chinese Journal of Interventional Cardiology

基　　金：首都医学发展科研基金(2009-3261)

摘　　要：目的探讨经皮冠状动脉介入治疗(PCI)后冠心病心绞痛患者生存质量的影响因素。方法纳入2013年3月至2014年3月北京市平谷区医院医疗保健部行PCI的冠心病心绞痛患者146例作为观察组,选择同期收治的100例冠心病心绞痛未行PCI的患者作为对照组,运用西雅图心绞痛调查量表(SAQ)对观察组患者治疗前24 h、治疗后5个月以及对照组患者入院后5 d的生存质量进行评分;观察组患者术后各影响因素首先采取单因素分析,然后进行Logistic多因素回归分析。结果观察组治疗前SAQ各维度评分(除疾病认知程度外)均显著低于对照组(P<0.05),而治疗后评分均显著高于对照组(P<0.05);观察组患者治疗5个月后SAQ各维度评分均较治疗前显著提高,差异具有统计学意义(P<0.05);合并高血压病、合并糖尿病、病变血管数、吸烟、饮酒以及术后重返工作岗位对PCI术后患者生存质量影响单因素分析中,差异有统计学意义(P<0.05);对上述单因素分析具有统计学意义的各因素进行Logistic回归分析,结果显示,术后重返工作岗位、病变血管数、合并高血压病及是否吸烟具有统计学意义(P<0.05)。结论术后重返工作岗位、病变血管数、合并高血压病以及是否吸烟是影响冠心病心绞痛患者PCI术后生存质量的独立因素。Objective To investigate the influencing factors on quality of life in patients with angina pectoris after coronary intervention.Methods Between March 2013 to March 2014 in Beijing Pinggu District Hospital 146 CAD patients with angina pectoris who received PCI were enrolled in the observation group,and another 100 patients with angina pectoris without coronary intervention were included as the control group.The Seattle Angina Questionnaire（SAQ） was used for assessment of quality of life at 24 hrs pre-PCI and 5 months after PCI in the observation group and the SAQ was used in the control group 5 days after admission.The influencing factors were further studied through urivariate analysis followed by logistic regression analysis.Results The scores of different in scales on the SAQ were lower in the observation group than in the control（P〈0.05） before PCI but were higher than the control group in all 5 scales after PCI（P〈0.05）.Within the observation group,the scores in all scales on the SAQ were increased in 5months after PCI when compared to pre-PCI scores（P〈0.05）.Co-morbidities with hypertension,diabetes,number of diseased ressels,smoking,alcohol consumption and return to work after PCI all showed influence on quality of life after PCI on univariate analysis（all P〈0.05）.Logistic regression analysis showed that return to work after PCI,the number of diseased vessels,presence of hypertension and smoking were the independant influencing factors（P〈0.05）.Conclusions Returning to work,the number of diseased coronary arteries,hypertension and smoking history were independent factors affecting the quality of life in patients with angina pectoris after PCI.

关 键 词：经皮冠状动脉介入治疗 冠心病心绞痛 生存质量 影响因素 

分 类 号：R654.2[医药卫生—外科学]