介入治疗和外科开胸手术治疗小儿室间隔缺损的临床效果对比  

Comparative Study for Clinical Effect on Ventricular Septal Defect in Children between Interventional Treatment and Surgical Open Thoracic Operation

作　　者：陈定柱[1] 张奕[1] 刘进平[1] 林丽华[1] 沈斐敏[1] 

机构地区：[1]福建医科大学附属漳州市医院,363000

出　　处：《实用心脑肺血管病杂志》2015年第8期54-56,共3页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

摘　　要：目的比较介入治疗与外科开胸手术治疗小儿室间隔缺损(VSD)的临床效果。方法选取2012—2014年在福建医科大学附属漳州市医院治疗的VSD患儿63例,根据患儿治疗方式不同分为介入治疗组(n=30)和外科开胸手术组(n=33)。介入治疗组患儿接受经导管室间隔缺损封堵术,外科开胸手术组患儿接受外科开胸手术。两组患儿术后7 d内均行超声心动图及心电图检查,术后随访6个月,比较两组患儿治疗情况(包括手术成功率、手术时间及术后住院时间)、术后残余分流发生情况及术后并发症(心律失常、新发瓣膜返流)发生情况。结果两组患儿手术成功率比较,差异无统计学意义(P>0.05)。介入治疗组患儿手术时间和术后住院时间均短于外科开胸手术组(P<0.05)。外科开胸手术组患儿术后残余分流、心律失常和新发瓣膜返流发生率均低于介入治疗组(P<0.05)。结论介入治疗与外科开胸手术治疗VSD的临床效果相当,但外科开胸手术术后残余分流发生率低、并发症少,介入治疗操作时间短、创伤小、术后恢复快且术后不留瘢痕。Objective To compare the clinical effect on ventricular septal defect in children between interventional treatment and surgical open thoracic operation. Methods From 2012 to 2014,a total of 86 children with ventricular septal defect（ VSD） were selected in Zhangzhou Hospital Affilicated to Fujian Medical University,and they were divided into A group （n=30）and B group（n=33）according to therapeutic methods. Children of A group were treated by transcatheter ventricular septal defect occlusion,while children of B group were treated by surgical open thoracic operation. Within 7 days after operation, echocardiography and electrocardiogram examinations were carried out, and both groups were followed up for 6 months, therapeutic conditions（including operation successful rate,operation duration and postoperative hospital stays）,incidence of residual shunts and postoperative complications （ arrhythmia and new valve regurgitation ） were compared between the two groups. Results No statistically significant differences of operation successful rate was found between the two groups （ P〉0. 05 ）. Operation duration and postoperative hospital stays of A group were statistically significantly shorter than those of B group （P〈0. 05）. The incidence of residual shunts,arrhythmia and new valve regurgitation of B group was statistically significantly lower than that of A group, respectively （ P〈0. 05 ）. Conclusion Interventional treatment has similar clinical effect on ventricular septal defect in children with surgical open thoracic operation,but the incidence of residual shunts and postoperative complications of surgical open thoracic is relatively less,while operation duration of interventional treatment is relatively shorter, the trauma is more milder,the recovery time is shoreer and without scars.

关 键 词：室间隔缺损 介入治疗 外科手术 疗效比较研究 

分 类 号：R541.1[医药卫生—心血管疾病]