PKP联合抗骨质疏松药物治疗老年椎体压缩性骨折的疗效观察  

Percutaneous kyphoplasty in combination with anti-osteoporotic drugs for elderly patients with vertebral compression fractures

作　　者：王臻[1] 张斌[1] 欧阳明[1] 

机构地区：[1]扬州大学医学院附属六合医院,南京211500

出　　处：《国际医药卫生导报》2015年第19期2849-2852,共4页International Medicine and Health Guidance News

摘　　要：目的 探讨经皮球囊扩张椎体后凸成形术（percutaneous kyphoplasty,PKP）联合抗骨质疏松药物治疗老年椎体压缩性骨折的临床疗效.方法 对2014年1月至2015年1月于我科行PKP联合抗骨质疏松药物治疗的46例老年椎体压缩性骨折患者进行回顾性分析,比较治疗前后伤椎高度丢失百分比和Cobb角度的变化,采用视觉模拟评分法（Visual Analogue Score,VAS）评价疼痛程度,使用SF-36问卷调查患者满意度.结果 本组患者伤椎高度丢失百分比术前为（30.2±10.1）％,术后为（17.2±9.1）％;Cobb角度术前为（16.9±5.4）°,术后为（8.9±3.7）°;VAS评分术前为（7.6±1.2）分,术后为（2.5±0.9）分;SF-36评分术前为（169.5±31.7）分,术后为（353.7±44.3）分,以上指标术前、术后差异均具有统计学意义（P〈0.01）.3例患者出现骨水泥渗漏,但均无临床症状.无其他严重并发症出现.结论 PKP联合抗骨质疏松药物是治疗老年骨质疏松性椎体压缩骨折安全有效的方法.Objective To evaluate the clinical efficacy ofpercutaneous kyphoplasty （PKP） in the combination with anti-osteoporotic drugs for elderly patients with vertebral compression fractures.Methods The clinical data of 46 elderly patients suffering from vertebral compression fractures and treated with PKP and anti-osteoporotic drugs at our department from January, 2014 to January, 2015 were retrospectively analyzed.Vertebral compression ratio, Cobb＇s angle, visual analogue scale （VAS）, and patients＇ satisfactory degree were compared before and after the operation.Results All the patients tolerated the procedure and 44 of them were relieved in back pain in 72 hours.The vertebral compression ratio, Cobb＇s angle, VAS, and patients＇ satisfactory degree were improved from （30.2±10.1）%, （16.9±5.4）°,（7.6±1.2）, and （169.5±31.7）before the operation to （17.2±9.1）%, （8.9±3.7）°, （2.5±0.9）,and （353.7±44.3） after the operation （P〈0.01）.Cement leakage occurred in 3 cases but had no clinical symptoms.No other serious complication was observed.Conclusions PKP in the combination with anti-osteoporotic drugs for elderly patients with vertebral compression fractures is safe and effective.

关 键 词：经皮推体后凸成形术 骨质疏松 脊柱骨折 老年人 

分 类 号：R681[医药卫生—骨科学]