保山市15岁以上人群乙肝HBsAg、HBsAb血清学调查  

Serological survey analysis of hepatitis B surface antigen and surface antibody among population over 15 years old in Baoshan city

作　　者：赵丽娟[1] 王黎明[1] 张腾[1] 黄东升[1] 李庆芳[1] 段丽忠[1] 王生芳[1] 郑维斌[1] 

机构地区：[1]云南省保山市疾病预防控制中心,云南保山678000

出　　处：《现代预防医学》2015年第20期3789-3791,3808,共4页Modern Preventive Medicine

摘　　要：目的 了解保山市15岁以上人群乙型病毒性肝炎（简称乙肝）表面抗原、表面抗体水平,探讨乙肝感染情况及防控策略和措施。方法 采用多阶段分层随机抽样的原则,在保山市5个县区随机抽取15岁以上人群2 768人,调查基础数据,对抽取的血清用胶体金快速检测表面抗原（HBs A）g、表面抗体（抗-HBs）结果 2012年保山市15岁以上人群乙肝表面抗原、表面抗体阳性率分别为2.96%、23.16%;男性表面抗原、表面抗体阳性率分别为3.58%、24.72%,女性分别为2.45%、21.85%;各年龄段乙肝表面抗原阳性率、表面抗体保护率分别在2.4%~3.7%和18.6%~27.8%之间;农民表面抗原、表面抗体阳性率分别为3.03%,22.31%,非农民表面抗原、表面抗体阳性率分别为2.49%,22.57%;城区表面抗原、表面抗体阳性率分别为2.65%、23.26%,郊区表面抗原、表面抗体阳性率分别为6.54%、16.51%,山区表面抗原、表面抗体阳性率分别为1.52%、26.05%,城乡差异有统计学意义;隆阳区、腾冲县、施甸县、昌宁县、龙陵县表面抗原阳性率分别为2.42%、3.09%、2.75%、4.07%、2.50%,表面抗体阳性率分别为23.65%、34.00%、15.29%、25.18%、18.25%,差异有统计学意义。结论 保山市15岁以上人群乙肝表面抗原携带率较低,但乙肝疫苗保护率也较低。应充分发挥教育、卫生、社区、基层公共卫生服务的作用,加大对乙肝危害及接种乙肝疫苗好处的宣传力度,提高接种率。Objective The aim of this study was to understand the level of hepatitis B surface antigen and surface antibody among population over 15 years old in Baoshan city, and to discuss policies and methods needed for the control and prevention of hepatitis B. Methods A total of 2768 serum samples were collected by the means of multi-stage stratified random sampling from the residents above 15 years old. And based data were selected, while HBs Ag and anti-HBs Ab were tested in rapid test strip. Results Hepatitis B surface antigen and surface antibody positive rates were 2.96% and 23.16% among the population over 15 years old in Baoshan city. For male, surface antigen and surface antibody positive rates were 3.58% and 24.72%, respectively. For female, surface antigen and surface antibody positive rates were 2.45% and 21.85%, respectively. For different age groups, surface antigen and surface antibody positive rates were 2.4%-3.7% and 18.6%-27.8%, respectively. For farmer, surface antigen and surface antibody positive rates were 3.03% and 22.31%, respectively. For non-farmers, antigen and surface antibody positive rates were 2.49% and 22.57%,respectively. For urban residents, surface antigen and surface antibody positive rates were 2.65% and 23.26%. For suburban residents, surface antigen and surface antibody positive rates were 6.54% and 16.51%, respectively. For mountain residents, surface antigen and surface antibody positive rates were 1.52% and 26.05%, respectively. There was statistical significance in urban-rural areas. In Longyang district, Tengchong county, Shidian county, Changning county and Longling, surface antigen positive rates were2.42%, 3.09%, 2.75% 4.07% and 2.50%, respectively. The surface antibody positive rates for these counties were 23.65%, 34.00%,15.29%, 25.18% and 18.25%, respectively. There was statistical significance in county distribution. Conclusion In Bao Shan,hepatitis B surface antigen and hepatitis B vaccine protection was low. Attention should be paid to education, health, community,gras

关 键 词：乙肝 血清学 免疫保护水平 

分 类 号：R181.36[医药卫生—流行病学]