应用fNIRS技术对运动执行与运动想象脑激活模式的研究  

Brain activation modes during motor execution and motor imagery in healthy individuals by functional near infrared reflectance spectroscopy

作　　者：杜凯[1] 王莉[1] 冯正权[1] 张晔[1] 邱明国[1] 

机构地区：[1]第三军医大学生物医学工程系医学图像学教研室,重庆400038

出　　处：《第三军医大学学报》2015年第20期2017-2021,共5页Journal of Third Military Medical University

基　　金：国家自然科学基金面上项目(81171866);教育部留学回国人员科研启动基金(2012)~~

摘　　要：目的研究在运动执行和运动想象任务刺激下大脑功能激活模式,探讨运动想象的神经机制。方法选择23名右利手正常人作为被试,运用近红外光学脑成像系统采集在运动执行与运动想象任务下脑部氧合血红蛋白、去氧血红蛋白和总血红蛋白浓度相对变化量,并运用统计学检验和模型估计方法进行数据分析。结果左手运动执行时激活脑区为右侧SMA、PMC和M1区,左手运动想象时激活的脑区为右侧PMC区,右手运动执行时激活脑区为左侧PMC、M1和SMA区,右手运动想象时激活的脑区为左侧PMC和M1区。结论运用近红外光学脑成像能够很好显示刺激任务下脑功能激活状态,在运动想象和运动执行时大脑皮层激活部位及强度相似。Objective To research the brain activation modes during motor execution and motor imagery, and explore the neuromechanism of motor imagery. Methods Twenty-three healthy right-handed persons were recruited, and the contents of oxyhemoglobin, deoxyhemoglobin and total hemoglobin in the brain during motor execution and motor imagery were measured by functional near infrared reflectance spectroscopy （fNIRS）, and the data were analyzed by statistical test and model estimation. Results The activating areas during left-hand motor execution were right-side supplementary motor area （ SMA）, premoter cortex （ PMC ） and primary motor （M1） areas, and the activating area during left-hand motor imagery was right-side PMC area. The activating areas during right-hand motor execution were left-side PMC, M1 and SMA areas, and the activating areas during right-hand motor imagery were left-side PMC and M1 areas. All the activating areas were contralateral cerebral regions. Conclusion fNIRS can show the cerebral activation states in the stimulus tasks, and the cerebral cortex activating areas and strength are similar during motor execution and motor imagery.

关 键 词：功能性近红外光谱技术 运动想象 运动执行 脑激活模式 氧合血红蛋白 

分 类 号：R338.4[医药卫生—人体生理学] R445.7[医药卫生—基础医学]