超脉冲二氧化碳点阵激光联合微针治疗痤疮瘢痕的临床效果  

Clinical efficacy of fractionated ultrapulse carbon dioxide laser combined with microneedle for the treatment of acne scars

作　　者：杨凌云[1] 王敏[1] 龚雪[1] 李其爱[1] 晏洪波[1] 

机构地区：[1]广州军区武汉总医院皮肤科,430000

出　　处：《中华医学美学美容杂志》2015年第5期260-263,共4页Chinese Journal of Medical Aesthetics and Cosmetology

摘　　要：目的 探讨超脉冲二氧化碳点阵激光联合微针治疗面部痤疮凹陷性瘢痕的疗效和安全性.方法 将86例面部痤疮凹陷性瘢痕患者按治疗方法不同完全随机分为两组,观察组采用点阵二氧化碳激光和微针联合治疗;对照组仅用超脉冲二氧化碳点阵激光治疗.治疗间隔1～3个月,治疗2～8次.治疗前、后对两组的痤疮瘢痕权重评分（ECCA）、总有效率及不良反应进行比较.结果 两组治疗前、后ECCA评分均明显下降,其中观察组评分从（61±11）分降至（45±15）分,对照组评分从（57±14）分降至（40±16）分,差异均有统计学意义（均P＜0.05）.两组疗效均随治疗次数增多而明显提高.观察组46例的总有效率分别为81.8％（18/22）、100.0％（24/24）,对照组40例的总有效率分别为80.0％（16/20）、100.0％（20/22）,两组差异无统计学意义（P＞0.05）.但在达相似疗效时,治疗周期观察组为（6.8±1.6）个月,对照组为（20.8±4.6）个月,两组差异有统计学意义（P＜0.05）.观察组2例、对照组5例术后出现红斑和色素沉着.结论 超脉冲二氧化碳点阵激光联合微针和单纯超脉冲二氧化碳点阵激光治疗面部痤疮凹陷性瘢痕均有较好疗效,但联合治疗见效快,并发症少,治疗周期缩短.Objective To investigate the clinical efficacy of fractionated ultrapulse carbon dioxide laser combined with microneedle for depressed acne scars.Methods Totally 86 patients with depressed acne scar were randomly divided into 2 groups：the treatment group received fractionated ultrapulse carbon dioxide laser combined with microneedle technology and the control group only received fractionated ultrapulse carbon dioxide laser.The treatment interval was 1 to 3 months,and the whole course was 2-8 times.The total effective rate and the adverse reaction were analyzed in the facial acne scar.Results The surface of depressed acne scars was significantly improved.ECCA score of all patients declined obviously after treatment,the score of the treatment group declined from 61± 11 to 45± 15,and the control group declined from 57± 14 to 40± 16.There were significantly statistical differences in the results of each group （P〈0.05）.More treatment times resulted in better surface improvement.The total effective rate were 81.8% （18/22） and 100% （24/24） in the treatment group,and 80.0% （16/20） and 100% （20/22） in the control group.The course was 6.8± 1.6 months in the treatment group and 20.8±4.6 months in the control group （P〈0.05） to get a similar satisfied result.There were no obvious adverse reactions except two cases of erythema and pigmentation in the treatment group and 5 cases in the control group.The former was with less adverse reactions.Conclusions Ultrapulse carbon dioxide laser combined with microneedle technique is effective for facial acne scars,with less complications and shorten treatment course.

关 键 词：点阵激光 微针 痤疮瘢痕 

分 类 号：R758.733[医药卫生—皮肤病学与性病学]