钝性胸部创伤后血流动力学变化及意义  

Changes and significances of hemodynamics after blunt trauma of chest in rabbits

作　　者：闵家新[1] 朱佩芳[2] 王正国[2] 

机构地区：[1]第三军医大学附属新桥医院胸外科,重庆400037 [2]第三军医大学附属大坪医院野战外科研究所第四研究室,重庆400042

出　　处：《第三军医大学学报》2002年第8期947-948,共2页Journal of Third Military Medical University

基　　金：国家自然科学基金资助重点项目 ( 396 30 330 )

摘　　要：目的　探讨钝性胸部创伤 (BCT)后血流动力学变化及意义。方法　选取兔 2 0只 ,经右颈总动脉插管至左心室测左室压力 ,左股动脉插管测平均动脉压 (MAP)。采用BIM Ⅱ型生物撞击机致成BCT模型 ,分别在伤前、伤后 1、2、4、6、8、12、2 4h监测血流动力学变化。结果　BCT后心脏功能受到损害 ,左心室收缩功能在伤后 4h～ 6h恢复至伤前水平 ,而舒张功能在伤后 2 4h不能恢复至伤前水平。结论　BCT后血流动力学发生明显改变 ,左心室以舒张功能障碍为主 。Objective To explore the changes and the significances of the hemodynamics after blunt chest trauma(BCT)in rabbits. Methods A total of 20 rabbits were inflicted with BIM Ⅱ Bio impactor to establish the model of BCT. Changes of the hemodynamics pre injury and in 1, 2, 4, 6, 8, 12 and 24 h post injury were observed. Results The systolic function of left ventricle was impaired and recovered during 4～6 h after BCT, while its diastolic function was impaired too but not recovered 24 h after BCT. Conclusion Hemodynamic parameters are changed after BCT. Attention should be paid to the systolic dysfunction of left ventricle in the treatment of patients after BCT.

关 键 词：创伤 钝性胸部创伤 心脏功能 血流动力学 BCT 

分 类 号：R655[医药卫生—外科学]