世界奶牛乳房炎疫苗研究的知识图谱分析  

Knowledge Mapping Analysis on Global Bovine Mastitis Vaccine Research

作　　者：杨峰[1] 王玲[1] 王旭荣[1] 李新圃[1] 罗金印[1] 张世栋[1] 李宏胜[1] 

机构地区：[1]中国农业科学院兰州畜牧与兽药研究所农业部兽用药物创制重点实验室甘肃省新兽药工程重点实验室,兰州730050

出　　处：《中国畜牧兽医》2015年第10期2762-2771,共10页China Animal Husbandry & Veterinary Medicine

基　　金：甘肃省省青年科技基金计划项目(145RJYA311);中央级公益性科研院所基本科研业务费专项资金项目(1610322015007);"十二五"国家科技支撑项目(2012BAD12B03)

摘　　要：为了展示世界奶牛乳房炎疫苗领域的整体研究状况和研究热点,基于CitespaceⅢ研究了1995—2015年Web of ScienceTM核心合集数据库所收录的奶牛乳房炎疫苗相关的4 205条科技文献,分析了年度发文量,绘制了主要国家、机构、作者、被引期刊、被引文献及关键词的知识图谱。结果发现,奶牛乳房炎疫苗研究领域的年度发文量从1995至2012年持续上升,2013年发文量开始呈下滑的趋势;研究奶牛乳房炎疫苗的国家和机构主要分布在美洲、欧洲和亚洲,大学是该研究领域的主要研究机构;奶牛乳房炎疫苗研究领域的热点集中于:病原菌的分离鉴定、耐药性和致病机理;受染奶牛机体自身的免疫应答及相关的调控因子;预防和治疗乳房炎的最佳时期;有效抗原的筛选。该领域未来一段时期的研究方向将侧重于NF-κB和生物被膜的相关研究。To understand the overall status and focus of bovine mastitis vaccine research,knowledge maps of mainly country,institution,author,cite journal,cite reference,keyword,year distribution of publications on research of bovine mastitis vaccine were studied by CitespaceⅢ,which collected 4 205 international scientific literatures download from Web of ScienceTMcore collection（1995to 2015）.The results showed that in research field of bovine mastitis vaccine,the number of published papers increased from 1995 to 2012,but it began to decrease in 2013;Countries and institution involved in the research were mainly distributed in America,Europe and Asia,and universities played important roles in this field;In addition,the research field were mainly focus on：Isolation and identification of pathogens,detection of drug susceptibility and pathogenesis exploration;Immune response and relevant regulatory factor in infected dairy cows;Best period for prevention and treatment;Screening for candidate antigen.In future time,studies will pay more attention on research of NF-κB and biofilm in field of bovine mastitis vaccine.

关 键 词：奶牛乳房炎 疫苗 知识图谱 Web of ScienceTM核心合集 CitespaceⅢ 

分 类 号：S823[农业科学—畜牧学]