PM2.5对呼吸系统的病理影响及中医药防治  

Pathological effects of PM2.5 to respiratory system and preventive treatment using traditional Chinese medicine

作　　者：秦玉英[1,2] 刘颖[2] 敬岳[2] 谷明杰 蔡哲[1] 张洪春[1] 

机构地区：[1]中日友好医院,北京100029 [2]北京中医药大学,北京100029

出　　处：《中华中医药杂志》2015年第10期3477-3482,共6页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：中日友好医院2013年院级科研基金项目(No.2013-MS-51)~~

摘　　要：PM2.5是空气动力学直径≤2.5μm的颗粒物,最主要的来源是煤炭燃烧、机动车尾气、烟草烟雾等,特征是体积小、重量轻,在大气中滞留时间长,可以携带有毒有害污染物进行远距离传输,对呼吸疾病发病率、住院率、病死率存在明显影响,引起氧化应激产生活性氧物质、炎性反应,影响机体特异性免疫反应及非特异性免疫反应,损伤肺巨噬细胞功能,导致肺组织和气道损伤。为了人类的健康,减少PM2.5环境污染带来的危害,中医药"治未病"的思想为防治环境污染相关呼吸道疾病可开拓新的思路。PM2.5（particulate matter 2.5） is the particle whose aerodynamic diameter less than or equal to 2.5μm,that most comes from coal combustion,vehicle exhaust,tobacco smoke and so on.PM2.5 with the character of small volume,light weight,and long residence in the atmosphere,can carry toxic and harmful pollutants in remote transmission,which obviously influences incidence of respiratory diseases,hospitalization rate and mortality,and last leads to lung tissue and airway injured by causing oxidative stress producing reactive oxygen substances,inflammation the reaction,affecting the body＇s specific immune response and non-specific immune response,damaging the function of pulmonary alveolar macrophages.In order to ensure human health and reduce the harm of environmental pollution caused by PM2.5,the idea of＇preventive treatment of disease in TCM＇ for the prevention and control of environmental pollution related respiratory disease may open up new ideas.

关 键 词：PM2.5 呼吸系统 氧化应激 炎性因子 免疫损伤 治未病 

分 类 号：R259[医药卫生—中西医结合]