补肾导浊颗粒治疗良性前列腺增生症65例的临床研究  

Clinical study of Bushen Daozhuo Granule in treating 65 cases of benign prostatic hyperplasia patients

作　　者：王勇[1] 孙大林[2] 金保方[2] 张新东[3] 夏国守[3] 徐福松[3] 

机构地区：[1]昆山市第一人民医院泌尿外科,昆山215300 [2]东南大学附属中大医院中西医结合男科,南京210009 [3]南京中医药大学第三附属医院,南京210001

出　　处：《中华中医药杂志》2015年第10期3775-3777,共3页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家自然科学基金项目(No.81273760;No.81473678);国家自然科学青年基金项目(No.81302969;No.81403402)~~

摘　　要：目的:探讨补肾导浊颗粒治疗良性前列腺增生症的疗效。方法:选择确诊的良性前列腺增生症(BPH)患者120例,随机分成两组。对照组患者服用多沙唑嗪(可多华)4mg,每晚1次;治疗组服用补肾导浊颗粒(每次200m L,每日2次)。两组分别在治疗前和治疗4周后行国际前列腺症状评分(IPSS)、生活质量评分(QOL)、最大尿流率测定(Qmax)、膀胱残余尿量(RU)和中医症候评分,并计算疾病、中医症候总疗效和总有效率。结果:与对照组相比,治疗组在IPSS、QOL、Qmax、RU等指标上均有明显改善(P<0.05),并且在疾病、中医症候的总疗效和总有效率均优于对照组(P<0.05)。结论:补肾导浊颗粒在改善BPH患者的下尿路症状及全身症状方面都发挥着重要作用,为临床治疗BPH提供一套切实有效的方法。Objective：To investigate the efficacy of Bushen Daozhuo Granule in treatment of benign prostatic hyperplasia（BPH）.Methods：One hundred and twenty cases of clinically diagnosed BPH patients were randomly assigned two groups.The control group received doxazosin（Cardura） 4mg,every night and the treatment group was given Bushen Daozhuo Granule（200mL each time,2 times every day）,both for 4 weeks.Before and after the treatment,the international prostate symptoms score（IPSS）,quality of life（QOL）,Qmax,bladder residual urine volume（RU） and TCM syndrome score were obtained,and the total curative effect and the total effective rate of diseases and syndromes were calculated.Results：Compared with the control group,the detection index of IPSS,QOL,Qmax,RU were significantly improved in treatment group（P〈0.05）.The total curative effect of TCM syndrome of the disease,and the total effective rate were improved in the treatment group,compared with the control group（P〈0.05）.Conclusion：The Bushen Daozhuo Granule plays an important role in improving lower urinary tract symptoms and systemic symptoms of BPH.This provides a set of practical and effective treatment for clinical treatment of BPH.

关 键 词：良性前列腺增生症 补肾导浊颗粒 国际前列腺症状评分 生活质量评分 膀胱残余尿量 最大尿流率 

分 类 号：R277.5[医药卫生—中医学]