络活喜治疗原发性高血压疗效的效果分析  

The Curative Effects Analysis of Norvasc Treatment of Essential Hypertension

作　　者：张风雷 

机构地区：[1]河南省周口市鹿邑真源医院介入科,河南周口477200

出　　处：《中国医药指南》2015年第29期20-21,共2页Guide of China Medicine

摘　　要：目的探讨络活喜治疗原发性高血压疗效的效果。方法选择2012年8月至2015年2月在我院诊治的高血压患者190例,根据随机抽签原则分为治疗组与对照组,每组95例。对照组口服替米沙坦片治疗,治疗组口服络活喜治疗,治疗8周。结果两组治疗后的收缩压与舒张压都呈现明显下降的趋势(P<0.05),同时治疗后治疗组的收缩压与舒张压都明显低于对照组(P<0.05)。两组治疗前后的静息状态肱动脉内径变化对比差异都无统计学意义,不过治疗后两组的加压后肱动脉内径扩张率都明显增加(P<0.05),且治疗后治疗组的加压后肱动脉内径扩张率明显高于对照组(P<0.05)。结论络活喜治疗原发性高血压具有很好的降压效果,能有效改善机体内皮功能,安全性也比较好,值得推广应用。Objective To investigate the curative effects of norvasc treatment of essential hypertension. Methods From August 2012 to February 2015, 190 cases of patients in our hospital for treatment of high blood pressure, according to the principle of random draw into the treatment group and the control group, 95 cases in the control group was treated with telmisartan treatment group oral treatment norvasc, all eight weeks of treatment. Results After treatment, both systolic and diastolic blood pressure showed significant downward trend （P〈0.05）, while the treatment group, systolic and diastolic blood pressure were significantly lower than the control group （P〈0.05）. Plus treatment group before and after treatment, the resting state of the brachial artery diameter changes contrast differences are not statistically significant, but the two groups after treatment pressurized expansion rate of brachial artery diameter increased significantly （P〈0.05）, and after treatment pressure brachial artery diameter after expansion rate was significantly higher （P〈0.05）. Conclusion Treatment of essential hypertension norvase has better antihypertensive effect, it can effectively improve the body＇s endothelial function, and its security is relatively good that should be widely applied.

关 键 词：络活喜 原发性高血压 替米沙坦片 内皮功能 

分 类 号：R544.1[医药卫生—心血管疾病]