妊娠期糖尿病孕妇血糖与妊娠结局的关系研究  

Study on the correlation between blood glucose and pregnancy outcome in pregnant women with gestational diabetes mellitus

作　　者：符怡[1] 

机构地区：[1]华中科技大学同济文昌医院产科,海南文昌571300

出　　处：《中国妇幼保健》2015年第30期5116-5118,共3页Maternal and Child Health Care of China

摘　　要：目的 考察妊娠期糖尿病（GDM）对妊娠结局的影响及不同程度血糖水平与不良妊娠结局发生的相关性。方法选取2010年1月~2013年1月该院住院治疗的GDM患者120例作为实验组,同期就诊正常孕妇120例作为对照组,比较两组患者的巨大儿、胎儿窘迫、胎位异常和妊娠期高血压疾病等异常妊娠结局发生率和不同血糖水平,GDM患者异常妊娠结局发生率。结果 实验组发生不良妊娠38例,总发生率为31.67%,对照组发生不良妊娠8例,总发生率为6.72%,实验组显著高于对照组,差异有统计学意义（χ2=28.50,P〈0.01）;与对照组相比,实验组在空腹血糖、餐后1 h血糖、餐后2 h血糖和餐后3 h血糖差异均有统计学意义（t=4.07,P〈0.01;t=18.42,P〈0.01;t=8.14,P〈0.01;t=2.24,P〈0.05）;GDM低危险组不良妊娠发生率显著低于GDM高危险组,差异有统计学意义（χ2=10.46,P〈0.01）,GDM中危险组低于GDM高危险组,差异有统计学意义（χ2=4.24,P〈0.05）。结论 GDM患者不良妊娠结局发生率显著上升,与GDM患者血糖水平呈正相关。Objective To explore the effect of gestational diabetes mellitus （GDM） on pregnancy outcome and the correlation between different degrees of blood glucose levels and occurrence of adverse pregnancy outcomes. Methods A total of 120 GDM patients trea- ted in the hospital from January 2010 to January 2013 were selected as experimental group, 120 normal pregnant women during the same period were selected as control group ; the incidence rates of abnormal pregnancy outcomes （ macrosomia, fetal distress, abnormal fetal position, and hypertensive disorder complicating pregnancy） in the two groups and the incidence rates of abnormal pregnancy outcomes among the GDM patients with different blood glucose levels were compared. Results In experimental group, 38 cases were found with adverse pregnancy outcomes, the total incidence rate was 31.67% ; in conti：ol group, 8 cases were found with adverse pregnancy outcomes, the total incidence rate was 6. 72%, the total incidence rate in experimental group was statistically significantly higher than that in control group （X2 = 28. 50, P〈0. 01 ） ; there were statistically significant differences in fasting blood glucose, postprandial one-hour, two-hour, and three-hour blood glucose levels between the two groups （t=4.07, P〈0. 01 ; t= 18. 42, P〈0. 01 ; t=8. 14, P〈0. 01 ; t = 2. 24, P〈0. 05） . The incidence rate of adverse pregnancy outcomes in low-risk GDM group was statistically significantly lower than that in high-risk GDM group （X2=10. 46, P〈0. 01 ） ; the incidence rate of adverse pregnancy outcomes in middle-risk GDM group was statistically significantly lower than that in high-risk GDM group （X^2 = 4. 24, P〈0. 05 ） . Conclusion The incidence rate of adverse pregnancy outcomes in GDM patients increases significantly, which is positively correlated with blood glucose levels of GDM patients.

关 键 词：妊娠期糖尿病 血糖 妊娠结局 相关性 

分 类 号：R714[医药卫生—妇产科学]