Research progress of acute coagulopathy of trauma-shock  

作　　者：Baiqiang Li Haichen Sun 

机构地区：[1]Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China [2]Research Institute of Neurosurgery, Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, China

出　　处：《Chinese Journal of Traumatology》2015年第2期95-97,共3页中华创伤杂志（英文版）

摘　　要：Acute coagulopathy of trauma-shock （ACoTS） occurs in 25% of patients with severe trauma in the early phase, and the mortality of those patients is four-fold higher than patients without coagulopathy. The pathophysiology of this complicated phenomenon has been focused on in recent years. Tissue injury and hypoperfusion, activated protein C and Complements play important roles in the early phase after trauma. While the use of blood products, hypothermia, acidosis and inflammation are the main mechanism in late phase. Supplementing coagulation factors and platelets to improve ACoTS are inefficient. Only positive resuscitation from shock and improving tissue hypoperfusion have expected benefits.

关 键 词：Acute coagulopathyoftrauma-shock ACoTS Trauma Shock 

分 类 号：S858.28[农业科学—临床兽医学] Q592.1[农业科学—兽医学]