草血竭低极性部位化学成分的气相色谱-质谱法分析  

Analysis of the low polarity components from Polygonum paleaceum by GC-MS

作　　者：杨艺茜 张薇[1] 陈海生[1] 

机构地区：[1]第二军医大学药学院,上海200433

出　　处：《药学实践杂志》2015年第5期434-435,444,共3页Journal of Pharmaceutical Practice

摘　　要：目的研究草血竭(Polygonum paleaceum Wall)低极性部位的主要化学成分。方法草血竭用乙醇提取,提取液回收乙醇后用石油醚萃取,采用气相色谱-质谱法(GC-MS)对草血竭低极性部位进行分析测定,与标准谱库进行比较分析,并用峰面积归一化法计算各成分的质量百分数。结果共检出40个化学成分,其中主要成分β-瑟林烯和反油酸乙酯含量较高。结论草血竭低极性部位主要成分为β-瑟林烯(59.32%)和反油酸乙酯(27.02%),并含有棕榈酸(4.18%)、13,27-cycloursan-3-one(2.55%)、顺式-11-二十碳烯酸(1.31%)等化学成分。Objective To investigate the low polarity compounds from Polygonum paleaceum Wall .Methods The ethyl alcohol extracts of Polygonum paleaceum Wall were extracted with petroleum ether .The components were separated and iden-tified by GC-MS and elucidated by the comparison with the standard mass spectral data .The relative contents in percentage were calculated using the area normalization method .Results 40 compounds were identified .Naphthalene and （E）-9-octadece-noic acid ethyl ester were the main components .Conclusion The low polarity components of Polygonum paleaceum Wall were mainly consisted of naphthalene and （E）-9-octadecenoic acid ethyl ester （27 .02% ） ,along with hexadecanoic acid （4 .18% ） , 13 ,27-cycloursan-3-one （2 .55% ） and cis-11-eicosenoic acid （1 .31% ） .

关 键 词：草血竭 低极性部位 气相色谱-质谱联用分析 

分 类 号：R917[医药卫生—药物分析学]