移植嗅鞘细胞修复神经损伤作用的研究进展  

Advances in Transplantation of Olfactory Ensheathing Cells for Nerve Injury Repair

作　　者：张文俊[1] 况荣华[2] 刘曾旭[3] 

机构地区：[1]南昌大学研究生院医学部,2013级南昌330006 [2]南昌大学期刊社,南昌330006 [3]南昌大学基础医学院解剖学教研室,南昌330006

出　　处：《南昌大学学报（医学版）》2015年第4期92-94,共3页Journal of Nanchang University：Medical Sciences

基　　金：国家自然科学基金(81260190);江西省自然科学基金(20132BAB205023);江西省教育厅科学技术研究项目(GJJ13159)

摘　　要：近年来细胞移植治疗疼痛的研究已成为医学研究的热点,其中嗅鞘细胞(olfactory ensheathing cell,OECs)最受关注,它具有中枢和外周神经胶质细胞的特性,既像雪旺氏细胞促进轴突的生长,又像星形胶质细胞那样能在中枢神经系统中存活,正是这种复合体性使其成为治疗神经损伤最佳候选细胞之一,本文对移植OECs修复神经损伤作用的研究进展进行综述。The treatment of pain with cell transplantation has become a focus of medical research.Among different candidate cells,olfactory ensheathing cells（OECs）raise considerable concerns due to their characteristics of glial cells of the central and peripheral nervous systems.OECs can not only promote axonal growth like Schwann cells,but also survive in the central nervous system like astrocytes.The property of complex makes them optimal candidate cells for the treatment of nerve injury.This review presents the research progress in transplantation of OECs for nerve injury repair.

关 键 词：嗅鞘细胞 细胞移植 神经损伤 

分 类 号：R651.3[医药卫生—外科学]