强心饮治疗左室射血分数正常的慢性心力衰竭临床研究  

Clinical Observation on Qiangxin Decoction for Treatment of Chronic Heart Failure with Normal Left Ventricular Ejection Fraction

作　　者：郭美珠 唐丽萍 黄国毅[2] 张莉娜[3] 

机构地区：[1]上海市宝山区中西医结合医院,上海201900 [2]上海中医药大学附属曙光医院 [3]上海交通大学医学院生物统计学教研室

出　　处：《中西医结合心脑血管病杂志》2015年第11期1252-1254,共3页Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

基　　金：上海市卫生局基金资助项目(No.ZYSNXD011-RC-XLXX-20110002)

摘　　要：目的观察强心饮治疗左室射血分数正常的慢性心力衰竭的临床疗效。方法将58例患者随机分为两组,治疗组28例,给予基础治疗加强心饮口服,对照组30例给予基础治疗,10d为一个疗程。观察两组患者治疗前后N末端脑钠肽前体(NT-Pro-BNP)差值占比、心功能、中医证候积分、生活质量积分。结果强心饮有明显改善NT-pro-BNP,提高心功能,改善临床症状,改善生活质量积分的作用。结论强心饮治疗左室射血分数正常的慢性心力衰竭有效与改善NT-pro-BNP含量有关。强心饮疗效确切,服用安全,无不良反应。Objective To evaluate the effect of Qiangxin decoction（QXD）for treatment of chronic heart failure（CHF）patients with normal left ventricular ejection fraction（LVEF）.Methods Fifty-eight CHF patients with normal LVEF were randomly divided into two groups：The control group（n =30）treated with routine treatment,and the treatment group（n =28）treated with QXD in the basis of routine treatment for 10 days.The N-terminal pro-brain natriuretic peptide（NT-proBNP）level,cardiac function,integration of TCM syndrome and life quality score were observed.Results The NT-proBNP,cardiac function,integration of TCM syndrome and life quality were improved.Conclusion QXD is effective in treating CHF patients with LVEF,which can improve NT-proBNP.

关 键 词：慢性心力衰竭 左室射血分数正常 强心饮 

分 类 号：R259[医药卫生—中西医结合]