ADC联合DWI鉴别中枢神经细胞瘤与室管膜瘤的诊断价值  

The diagnostic value of ADC combined with DWI in the differentiation of the central neurocytoma and ependymoma

作　　者：王朝艳[1] 程敬亮[1] 聂云飞[1] 庞贝贝[1] 阎静[1] 宋一民[1] 

机构地区：[1]郑州大学第一附属医院磁共振科,郑州450052

出　　处：《放射学实践》2015年第10期1011-1015,共5页Radiologic Practice

摘　　要：目的:利用磁共振成像ADC值的测定,联合DWI磁共振成像探讨中枢神经细胞瘤与室管膜瘤的鉴别诊断。方法:回顾性分析本院经手术及病理检查证实的发生于侧脑室内,15例中枢神经细胞瘤和15例室管膜瘤患者常规MRI平扫、增强、DWI信号强度,并测量肿瘤实质病变的平均ADC值,观察比较两组肿瘤的DWI信号强度和ADC值,运用ROC曲线评价ADC值的诊断价值,统计学分析采用两样本t检验。结果:15例中枢神经细胞瘤DWI上均呈高或稍高信号,ADC均值(0.69±0.11)×10-3 mm2/s;15例室管膜瘤DWI上12例呈等或稍高信号,3例呈低信号,ADC均值(1.10±0.24)×10-3 mm2/s,两组肿瘤的平均ADC值比较具有统计学意义(P<0.01)。ADC值诊断中枢神经细胞瘤的灵敏度为100%,特异度为92.9%。结论:磁共振成像ADC值的测定辅助DWI信号强度有利于提高中枢神经细胞瘤和室管膜瘤的术前诊断及鉴别诊断。Objective：To study the diagnostic value of combining MRI ADC value with DWI signal density to differentiate the central neurocytoma and ependymoma.Methods：DWI signal intensity of MRI scan including plain scan and enhancement for 15 cases of central neurocytoma and 15 cases of ependymoma confirmed by operation and pathological examination in our hospital were retrospectively analyzed.The mean ADC value of the tumour was measured,the DWI signal indensity and ADC value between the two groups were compared,the diagnostic value of ADC value by ROC curve was evaluated,and two sample t tests were statistically analyzed.Results：In 15 cases of neurocytoma DWI showed high or slightly higher signal,ADC mean was（0.69±0.11）×10-3 mm2/s;In 12 from 15cases of ependymoma,DWI showed equal or slightly higher signal,3cases showed low signal,ADC mean was（1.10±0.24）×10-3 mm2/s.The comparison of ADC mean values betweeen the two groups showed significant difference（P〈0.01）.The sensitivity of ADC value for central neurocytoma diagnosis was 100% and the specificity was 92.9%.Conclusion：MRI ADC value combined with DWI signal density is beneficial to the preoperative diagnosis and differential diagnosis between central neurocytoma and ependymoma.

关 键 词：磁共振成像 神经细胞瘤 中枢 室管膜瘤 

分 类 号：R445.2[医药卫生—影像医学与核医学] R730.264[医药卫生—诊断学]