戒烟对浙江省海宁市某医院男性冠心病患者血脂代谢的影响  

Influence of Quitting Smoking on Lipid Metabolism in Male Patients with Coronary Heart Disease

作　　者：乔红元[1] 

机构地区：[1]浙江省海宁市中医院,海宁314400

出　　处：《医学与社会》2015年第10期72-74,共3页Medicine and Society

摘　　要：目的:了解冠心病患者戒烟后血脂代谢的变化。方法:选取浙江省海宁市某医院80例有吸烟史的冠心病患者随机分为戒烟组和吸烟组,每组40例,分别在戒烟第0个月、3个月、6个月及12个月检测血清血脂水平,并观察2组患者主要心血管事件发生率。结果:冠心病患者戒烟第3个月、6个月、12个月血清TC、TG、LDL-C较戒烟第0个月下降(P<0.05﹚,血清HDL-C水平较戒烟第0个月显著升高(P<0.05),与吸烟组比较差异具有统计学意义(P<0.05)。经过12个月随访观察,戒烟组与吸烟组冠心病患者均未出现心源性死亡事件;2组心血管事件发生率无显著性差异(P>0.05);戒烟组再住院率为7.5%,显著低于吸烟组(25.0%),差异具有统计学差异(P﹤0.05)。结论:戒烟能在较短时间内降低冠心病患者血清TC、TG、LDL-C水平,升高血清HDL-C水平,减少冠心病患者再住院率。Objective： To understand the changes of lipid metabolism in male patients with coronary heart disease after smoking cessation. Methods： 80 cases with coronary heart disease who were smoking were randomly divided into two group - smoking cessation group and control group, and each group had 40 cases. Lipids were monitored after 3 months, 6 months and 12 months in quitting smoking, and the influence of coronary events was investigated. Results： Serum TCI TG and LDL - C decreased after 3 months, 6 months and 12 months in smoking cessation （ P 〈 0.05 ） while HDL - C significantly increased （ P 〈 0.05 ）, compared with the control group. After 12 - month follow - up, cardiac death did not occur in patients of both groups. The rate of cardiovascular event had no significant difference between two groups （ P 〉 0.05 ）. The re - hos- pitalization rate of smoking cessation group was 7.5% , which was significantly lower than 25% of the control group （ P 〈 0.05 ）. Conclusion ： Serum TC, TG and LDL - C can be reduced and serum HDL - C can be risen in a relatively short time after smoking cessation, and the rate of re - hospitalization can be reduced in patients with coronary heart disease.

关 键 词：戒烟 冠心病 血脂代谢 

分 类 号：R197.1[医药卫生—卫生事业管理]