6种硫酸盐类矿物药中红外鉴别  

Comparison of Sulfate Mineral Medicines by Infrared Spectrum

作　　者：闫蔚[1] 曾柏淋 王淑美[1] 孟江[1] 梁生旺[1] 

机构地区：[1]广东药学院中药学院国家中医药管理局中药数字化质量评价技术重点研究室广东高校中药质量工程技术研究中心,广州510006

出　　处：《中国实验方剂学杂志》2015年第20期63-66,共4页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家中医药管理局中医药行业科研专项(201207004-7)

摘　　要：目的：对不同硫酸盐类矿物药进行中红外鉴别,为规范其质量控制提供参考。方法：用傅里叶变换红外光谱测定仪测定《中国药典》收录的6种硫酸盐类矿物药（石膏、芒硝、白矾、玄明粉、煅石膏、枯矾）,在400~4 000 cm-1内进行红外图谱扫描,比较分析6种硫酸盐类矿物药的中红外图谱异同点;测定玄明粉和无水硫酸钠的红外图谱,比较差异性。结果：在400~4 000 cm-1,由于同属于硫酸盐类矿物药,其中红外图谱具有共性,同时也因为其形成原理和阳离子的差异,峰形、峰数及透过率存在区别,红外可以用来鉴别不同类型的硫酸盐矿物药。玄明粉和无水硫酸钠的红外导数光谱具有差异性。结论：该方法简单、便捷,对矿物药乃至中药材的市场监控提供一定的参考意义。Objective： To identify different kinds of sulfate mineral medicines by infrared spectrum and provide the reference to regulate quality control. Method： Six different kinds of sulfate mineral medicines（ plaster,glauber＇s salt,alum,Natrii Sulfas Exsiccatus,Calcined Gypsum and Withered Alum） on Chinese Pharmacopoeia were identified with the use of FTIR,and their similarities and differences in the infrared spectrum were compared and analyzed by infrared spectrum scanning between 400 and 4 000 cm-1; infrared spectrum was measured and compared for Natrii Sulfas Exsiccatus and Sodium sulfate anhydrous. Result： Between 400 and4 000 cm-1,infrared spectrum has similarities because all of them are sulfate mineral medicines; however,due to the differences of forming mechanism,ions,peak shape,peak number and transmittance rate,infrared can be used to identify the different kinds of sulfate mineral medicines. There was difference in derivative infrared spectrum between Natrii Sulfas Exsiccatus and Sodium sulfate anhydrous. Conclusion： The method is simple,convenient,and provides certain reference for the market supervision of mineral medicines and even traditional Chinese medicinal materials.

关 键 词：傅里叶变换 中红外鉴别 石膏 芒硝 白矾 玄明粉 煅石膏 枯矾 

分 类 号：R284.1[医药卫生—中药学]