创伤及急性炎症患者血清肿瘤相关物质的变化及其临床意义  

SERUM LEVEL CHANGE OF TUMOR RELALED FACTORS IN PATIENTS WITH MECHANICAL TRAUMA AND ACUTE INFLAMMATION AND ITS CLINICAL SIGNIFICANCE

作　　者：张喜平[1] 费旭昭 程琪辉[3] 曾小澜[3] 刘效恭[1] 

机构地区：[1]西安交通大学第二医院 [2]西安市中医医院 [3]山西省肿瘤医院

出　　处：《解放军医学杂志》2002年第8期728-729,共2页Medical Journal of Chinese People's Liberation Army

摘　　要：研究机械性创伤及急性感染性炎症患者血清肿瘤相关物质 (TSGF)的变化 ,探讨其原因及临床意义。以 4 0例正常成年人作正常对照组 ,测定了 6 0例机械性创伤患者 (39例轻度 ,2 1例重度 )及 37例急性感染性炎症患者于创伤或感染后第 1、3和 12天时的血清TSGF的含量。结果显示 ,创伤或感染后第 1天和第 3天 ,患者血清TSGF的含量均明显高于正常对照组 (P <0 0 5 ,P <0 0 1) ,第 12天时重度创伤及急性炎症患者血清TSGF的含量仍明显高于正常对照组 (P <0 0 1) ,而轻度创伤患者与正常对照组比较差异无显著性意义 (P >0 0 5 )。To investigate the serum level changes of tumor related factors in patients with mechanical trauma and with acute inflammation, and to inquire into the possible reason and its clinical significance, TSGF level was detected on day 1, 3 and 12 after trauma or inflammation in 60 patients with mechanical trauma (39 with mild trauma and 21 with severe trauma) and 37 patients with acute inflammation, while 40 healthy persons were selected as the normal control group. TSGF serum level was significantly higher in patients with trauma and with infectious inflammation than that in normal control group on day 1 and day 3( P <0 05, P <0 01). On day 12, TSGF serum level in patients with severe trauma was significantly higher than that in normal control group ( P <0 01), but had no marked difference between patients with mild trauma and healthy persons ( P >0 05).The results suggest that TSGF is related with the recovery of trauma and inflammatory response.

关 键 词：急性炎症 创伤 损伤 肿瘤相关物质 

分 类 号：R641[医药卫生—外科学] R364.5[医药卫生—临床医学]