氨甲环酸对产后出血预防和治疗作用的研究进展  

Progress in Tranexamic Acid for Prevention and Treatment of Postpartum Haemorrhage

作　　者：周尚[1] 郭邑[2] 关怀[3] 

机构地区：[1]总后勤部卫生部药品仪器检验所,北京100071 [2]大连市妇产医院产科 [3]解放军第210医院妇产科

出　　处：《药物流行病学杂志》2015年第10期627-630,共4页Chinese Journal of Pharmacoepidemiology

摘　　要：产后出血(PPH)是产妇死亡的主要原因之一。产后给予子宫收缩药是目前唯一的预防方法。氨甲环酸(TXA)是一种抗纤溶药物,已经用于纤维蛋白溶解亢进所致的多种出血并证实有效。近年,TXA在产科领域的应用也逐渐增加,本文对TXA在阴道分娩和剖宫产分娩PPH的预防和治疗实践进行综述。Postpartum haemorrhage （PPH） is a major cause of maternal mortality. The administration of uterotonics after birth is the only intervention that has been shown to be effective in preventing PPH. Tranexamic acid （TXA）, an antifibrinolytic agent, has been widely used in many kinds of bleeding and demonstrated to be effective. In recent years, the use of TXA in obstetrics field has been increasing. This article reviewed progress in TXA for prevention and treatment of PPH.

关 键 词：氨甲环酸 产后出血 预防 治疗 

分 类 号：R973.1[医药卫生—药品]