Gold Nanoparticles for Cancer Theranostics  

作　　者：Hong Liang Huayu Tian Mingxiao Deng Xuesi Chen 

机构地区：[1]School of Chemist03, Northeast Normal University, Changchun 130024, China [2]Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China

出　　处：《Chinese Journal of Chemistry》2015年第9期1001-1010,共10页中国化学（英文版）

基　　金：This work was financially supported by the National Natural Science Foundation of China （Nos. 51222307, 51233004, 51390484, 21474104 and 51473029）, the Jilin Province Science and Technology Development Program （Nos. 20120306 and 20130521011JH）, and the Open Research Fund of the Key Laboratory of Advanced Technologies of Materials, Ministry of Education, Southwest Jiaotong University, Youth Innovation Promotion Association, CAS.

摘　　要：Gold nanoparticles have seen unprecedented development in the biomedical field, particularly for cancer ther- apy. They have received extensive attention because of their easy preparation, functionalization, biocompatibility, non-cytotoxicity, and detectability. Functionalized gold nanoparticles can be applied in the fields of drug and gene delivery, photothermal therapy, and bioimaging. This review introduces methods for preparing various shapes of gold nanoparticles and describes their current applications in the field of cancer treatment. Moreover, the review presents the development routes and current issues of gold nanoparticles in clinical theranostics.Gold nanoparticles have seen unprecedented development in the biomedical field, particularly for cancer ther- apy. They have received extensive attention because of their easy preparation, functionalization, biocompatibility, non-cytotoxicity, and detectability. Functionalized gold nanoparticles can be applied in the fields of drug and gene delivery, photothermal therapy, and bioimaging. This review introduces methods for preparing various shapes of gold nanoparticles and describes their current applications in the field of cancer treatment. Moreover, the review presents the development routes and current issues of gold nanoparticles in clinical theranostics.

关 键 词：gold nanoparticles cancer theranostics drug/gene delivery photothermal therapy BIOIMAGING 

分 类 号：TQ174.759[化学工程—陶瓷工业] S858.2[化学工程—硅酸盐工业]