大脑中线结构的断层解剖与三维重建研究  

The research of the sectional anatomy and three dimensional reconstruction of the cerebral midline structure

作　　者：麻雯熠 王单单[1] 张晓阳[1] 王春妹[1] 李云生[1] 

机构地区：[1]天津医科大学解剖学与组织胚胎学系,天津300070

出　　处：《中国临床解剖学杂志》2015年第5期527-530,共4页Chinese Journal of Clinical Anatomy

基　　金：天津医科大学重点学科项目资助(No.052-200010)

摘　　要：目的对大脑中线结构进行三维重建、第三脑室体积测量分析,为第三脑室前中部肿瘤切除的手术方法提供解剖学依据。方法选取10例经福尔马林固定的成年大脑标本(男、女各5例),经火棉胶包埋,分别制成厚500μm的水平位和冠状位火棉胶薄层切片,并对其进行观察、图像采集,选取其中一组女性水平位切片图像应用Amira软件进行三维重建,并对10例标本第三脑室进行体积测量。结果三维重建结果清晰显示了大脑中线结构胼胝体、穹窿、前连合、第三脑室、丘脑及丘脑间粘合的形态及毗邻关系,男性第三脑室平均体积为(1170.03±148.04)mm3,女性为(854.64±43.59)mm3,P>0.05,无统计学意义。结论对大脑中线结构的三维重建清晰的展示各个结构的立体形态和毗邻关系,为胼胝体-穹窿间手术入路切除第三脑室肿瘤提供了形态学依据,同时排除丘脑间粘合影响的第三脑室体积测量及男女体积差异性分析为脑室内镜手术操作空间提供了重要的参考价值。Objective To provide anatomical basis for surgical resection of the tumor in the anterior and middle of the third ventricle through the three-dimensional reconstruction of the brain midline structure and measurement of the volume of third ventricle. Methods 10 cases of formalin-fixed specimens of the adult brain were embedded by celloidin （5 males and 5 females） , successive horizontal and coronal sections with the thickness of 500μm were performed for observation and pictures collecting. The horizontal sections of a female were used for 3D reconstruction and the third ventricle volume in the samples were measured by Amirasoft. Results The results of the three-dimensional reconstruction clearly showed the shape and structure of the midline of the brain and adjacent relationship. The average volume of the third ventricle of male was （1170.03±148.04） mm3 and （854.64±43.59） mm3 for women （P〉0.05 ）, and no significant difference between men and women was detected. Conclusion The 3D reconstruction of the cerebral midline structure clearly shows the morphological structure and the interrelationship,which provides morphological basis for removal of the third ventricle tumor through tanscallosal-interfornical approach. Precise volume measurement of the third ventricle and comparison of differences between men and women provide an important reference data for endoscopic surgery of ventricle.

关 键 词：三维重建 第三脑室体积 火棉胶 胼胝体-穹窿间入路 

分 类 号：R323.1[医药卫生—人体解剖和组织胚胎学]