晚发型无乳链球菌脑膜炎的临床特征及治疗策略  

Clinical Features and Therapeutic Strategies of Late-onset Streptococcus Agalactiae Meningitis

作　　者：张胜[1] 罗序峰[1] 周涛[1] 付四毛[1] 朱建萍[1] 

机构地区：[1]南方医科大学附属中山市博爱医院儿科,广东省中山市528403

出　　处：《中国全科医学》2015年第29期3633-3635,共3页Chinese General Practice

摘　　要：无乳链球菌是婴儿期化脓性脑膜炎最为常见的致病菌之一,近年来,无乳链球菌脑膜炎发病率呈上升趋势。本研究回顾性分析6例无乳链球菌脑膜炎患儿临床资料,探讨无乳链球菌脑膜炎的临床特点及治疗策略。患儿临床表现为发热、惊厥、反应低下、前囟紧张或膨隆及呼吸不规则,部分患儿伴有硬膜下积液、脑出血、肝功能损害、低钠血症并发症。经药敏试验和脑脊液检查结果确定抗生素治疗方案。治疗4~6周6例患儿中治愈1例、好转4例、因感染性休克放弃治疗死亡1例。Streptococcus agalactiae is common pathogenic bacteria for infant suppurative meningitis. In recent years,the prevalence of streptococcus agalactiae meningitis is increasing. The paper made a retrospective analysis of the clinical data of6 children with streptococcus agalactiae meningitis and investigated the clinical features and therapeutic strategies of the disease.The clinical manifestations of the 6 children included fever,convulsion,decreased responsiveness,tensity or swell in bregma and irregular respiration. Subdural effusion,cerebral hemorrhage,liver function damage and hyponatremia as complication also occurred in some of the children. Antibiotic therapy was determined according to the results of drug sensitive test and cerebrospinal fluid examination. One child was cured and 4 children improved after 4-week to 6-week treatment. One child died due to the halt of treatment following septic shock.

关 键 词：脑膜炎 细菌性 无乳链球菌 临床特征 治疗 

分 类 号：R515.2[医药卫生—内科学]