孕妇糖化血红蛋白、血脂与巨大儿的相关性研究  

Study on the correlation of maternal glycosylated hemoglobin, blood lipid and macrosomia

作　　者：张春香[1] 毕素珍[2] 陈亭亭[1] 

机构地区：[1]山东省潍坊市中医院产二科,山东潍坊261041 [2]山东省潍坊市中医院杏埠分院妇产科,山东潍坊261041

出　　处：《中国现代医生》2015年第29期12-14,共3页China Modern Doctor

摘　　要：目的探讨孕妇糖化血红蛋白、血脂水平与巨大儿发生的相关性。方法选择2012年6月1日～2014年5月31日，在潍坊市中医院进行产前检查并住院分娩的301例孕妇。根据新生儿体重分为巨大儿组孕妇共176例（GDM巨大儿106例，非GDM巨大儿70例），正常体重儿组孕妇125例为对照组。孕37～39周测定孕妇糖化血红蛋白及血脂，对两组临床病历资料进行比较分析。结果（1）巨大儿组孕妇的HbA1c、TG、TC水平显著高于对照组（P〈0．05），而HDL-c、LDL-c水平差异无统计学意义（P〉0．05）；（2）巨大儿出生体重与孕妇的HbA1c、TG、TC水平呈正相关。结论孕妇糖化血红蛋白、血脂与巨大儿有相关性，监测孕妇HbA1c、血脂变化，可预防巨大儿的发生并有助于选择合适的方法终止妊娠。对减少母婴并发症有重大意义。Objective To investigate the correlation of maternal glycosylated hemoglobin, blood lipid levels and macro- somia. Methods A total of 301 pregnant women were involved in study, who were in Weifang Traditional Chinese hos- pital for prenatal examination and delivery from June 1st, 2012 to May 31st, 2014. According to the weight of newborn babies, these women were divided into macrosomia group176 cases（106 cases of GDM, 70 cases of no GDM） and normal group 125 cases. At 37 to 39 weeks of determination of glycosylated hemoglobin and blood lipids in pregnant women. The clinical data of two groups were compared and analyzed. Results （1）The HbA1c, TG, TC levels of the macrosomia group were significantly higher than the control group（P〈0.05）, but there were no significant differences in the levels of HDL-c, LDL-c between the pregnant women of the two groups（P〉0.05）. （2）Tbe birth weight of macrosomia and the HbA1c, TG, TC level of pregnant women were significantly positive correlation. Conclusion The glycosylated hemoglobin, blood lipid and macrosomia is associated. HbAlc, blood lipids monitoring, can prevent the occurrence of macrosomia and help to select a suitable method of termination of pregnancy, which can reduce the complication of mother andinfant.

关 键 词：巨大儿 妊娠期糖尿病 糖化血红蛋白 血脂 

分 类 号：R587.1[医药卫生—内分泌]