不同干馏时间所制竹沥对小鼠止咳化痰作用的影响  

Antitussive and Expectorant Effects of Different Carbonization Time Preparing Succus Bambusae in Mice

作　　者：罗怀浩[1] 蒋孟良[1] 金晓飞[1] 黎晓丽[1] 张斌贝 

机构地区：[1]湖南中医药大学,湖南长沙410208

出　　处：《中医药导报》2015年第19期33-35,共3页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：湖南省教育厅科研项目(0003000100801742);湖南省"十二五"重点学科中药学(湘教通[2011]76号);国家中医药管理局重点学科"中药炮制学"(国中医药人教发[2012]32号)

摘　　要：目的:观察不同干馏时间所制竹沥对小鼠止咳作用的影响,优选竹沥的最佳干馏时间,为竹沥的炮制提供科学、客观的工艺参数。方法:采用小鼠氨水引咳试验与小鼠气管酚红排泄试验,分别观察竹沥止咳与化痰的效果。结果:不同干馏时间所制竹沥均能不同程度的提高小鼠气管酚红分泌,延迟咳嗽潜伏期,减少咳嗽次数,当竹沥的炮制温度为400℃,时间为30 min时止咳化痰效果最佳。结论:干馏30 min的竹沥止咳化痰作用最佳。Objective： To observe the antitussive and expectorant effects of different carbonization time preparing Succus Bambusae in mice, to optimum carbonization time preferably succus bambusae and provide scientific, objective process parame-ters for succus bambusae processing. Methods： Ammonia inducing cough in mice test and mouse tracheal phenol red excretion test were applied to observe the antitussive and expectorant effect of succus bambusae respectively. Results： Different carboniza-tion time preparing succus bambusae could improve in various degrees of phenol red secretion of trachea, delay the cough incu-bation period, and decrease the frequency of cough; and succus bambusae processing temperature of 400 ℃, time is 30 min,which could provide the best effect of relieving cough and eliminating phlegm. Conclusion： Dry distillation 30 min capacity of antitussive and expectorant effects best.

关 键 词：竹沥 干馏法 止咳 化痰 小鼠 

分 类 号：R285.5[医药卫生—中药学]