磺酸官能化三苯基磷负载磷钨酸催化合成异戊酸正丁酯  

Catalytic Synthesis of Isoamyl Isovalerate by Phosphotungstic Acid Salt of Triphenyl(3-Sulfopropyl)Phosphonium as Catalysts

作　　者：陈可可 方苗利[1,2] 严巍 杜欢 谈忠琴 韩晓祥 励建荣[3] 

机构地区：[1]浙江工商大学应用化学系,杭州310035 [2]浙江医学高等专科学校基础部,杭州310053 [3]辽宁省食品安全重点实验室渤海大学,锦州121013

出　　处：《中国粮油学报》2015年第10期54-60,共7页Journal of the Chinese Cereals and Oils Association

摘　　要：以异戊酸和正丁醇为原料,酸性离子液体为催化剂,合成异戊酸正丁酯。选取醇酸物质的量比、反应时间、离子液体用量、带水剂量4个因素进行中心组合优化,运用响应面法得出合成异戊酸正丁酯的最佳工艺条件为:醇酸物质的量比1.15∶1,反应时间为80 min,离子液体用量为异戊酸的8%,带水剂量10 m L,在此最佳反应条件下异戊酸正丁酯的酯化率为89.52%,结果与模型预测值基本相符。将离子液体回收并重复使用5次,催化活性无明显降低,表明其具有良好的重复使用性。Butyl isovalerate has been synthesized by isovaleric acid and butanol with acidic ionic liquid as catalysts. Response Surface Methodology （RSM） was applied to optimize the synthesis of butyl isovalerate; the effects of various reaction conditions including alcohol/acid mole ratio, reaction time, ionic liquid amount and water carrying agent amount were also investigated. A Box - Behnken Experimental Design （BBD） was employed to search for the optimal yield of butyl isovalerate ; the optimized reaction conditions were n （butanol） ： n （ isovaleric acid） of 1.15： 1, reaction time of 80 min, amount of catalyst of 8% of acid and water - carrying agent of 10 mL. On the conditions, the best esterification rate could reach 89.52%, basically in line with the values predicted by the mathematical model. The ionic liquids could be recycled and reused for 5 times without obvious degradation in activity indicating that the catalysts have a good repetition.

关 键 词：离子液体 响应面法 异戊酸正丁酯 酯化率 

分 类 号：TQ655[化学工程—精细化工]