响应面分析法优化依兰香提取β-石竹烯工艺  

Optimization for β-caryophyllene Extraction from Cananga odorata by Response Surface Methodology

作　　者：郭玉华[1] 赵俊凌[1] 李晓花[1] 徐安顺[1] 元超[1] 

机构地区：[1]中国医学科学院-北京协和医学院药用植物研究所云南分所/西双版纳州傣药南药重点实验室,云南景洪666100

出　　处：《香料香精化妆品》2015年第4期13-16,19,共5页Flavour Fragrance Cosmetics

基　　金：景洪市科技三项经费--西双版纳州傣药南药重点实验室建设专项资助(编号201348)

摘　　要：在单因素试验基础上,以压力、时间、温度为响应因子,以β-石竹烯提取率为响应值,采用响应曲面法进行工艺优化预测,对依兰香中β-石竹烯的超临界CO2提取工艺进行优化。试验表明,影响β-石竹烯提取率的各因素的影响力由大到小顺序为压力、温度、时间,最佳提取工艺条件为提取压力369 MPa、提取温度60℃、提取时间4 h,此时β-石竹烯提取率为0.903 8%。验证试验结果与模型预测值基本相符,表明该工艺可用于依兰香中β-石竹烯的提取。On the basis of single factor experiments,pressure,time and temperature were selected as response factors,the extraction rate of β-caryophyllene as response value,response surface methodology was adopted to optimize the extraction conditions of β-caryophyllene,the supercritical fluid extraction（ SFE） conditions of β-caryophyllene from Cananga odorata were optimized. The results revealed that the impact factors on the extraction rate of β-caryophyllene sequenced in a descending order were pressure,temperature,time. The optimal extraction conditions were as follows： pressure 369 MPa,temperature 60 ℃,time 4 h,the extraction rate of β-caryophyllene was 0. 903 8%. The results of verified experiment were in accordance with prediction results by model,and this technology can be used in the extraction of β-caryophyllene from Cananga odorata.

关 键 词：依兰香 响应面分析法 β-石竹烯 萃取 

分 类 号：TQ654[化学工程—精细化工]