One-pot, solvent-free and efficient synthesis of 2,4,6-triarylpyridines catalyzed by nano-titania-supported sulfonic acid as a novel heterogeneous nanocatalyst  

作　　者：Elham Tabrizian Ali Amoozadeh Salman Rahmani Elham Imanifar Saeede Azhari Masoumeh Malmir 

机构地区：[1]Department of Organic Chemistry, Faculty of Chemistry, Semnan University

出　　处：《Chinese Chemical Letters》2015年第10期1278-1282,共5页中国化学快报（英文版）

基　　金：the Faculty of Chemistry of Semnan University for supporting this work

摘　　要：Nano titania-supported sulfonic acid（n-TSA） has found to be a highly efficient, eco-friendly and recyclable heterogeneous nanocatalyst for the solvent-free synthesis of 2,4,6-triarylpyridines through one-pot three-component reaction of acetophenones, aryl aldehydes and ammonium acetate. This reported method illustrates several advantages such as environmental friendliness reaction conditions,simplicity, short reaction time, easy work up, reusability of catalyst and high yields of the products. One new compound is reported too. Furthermore, the catalyst could be recycled after a simple work-up, and reused at least six times without substantial reduction in its catalytic activity.Nano titania-supported sulfonic acid（n-TSA） has found to be a highly efficient, eco-friendly and recyclable heterogeneous nanocatalyst for the solvent-free synthesis of 2,4,6-triarylpyridines through one-pot three-component reaction of acetophenones, aryl aldehydes and ammonium acetate. This reported method illustrates several advantages such as environmental friendliness reaction conditions,simplicity, short reaction time, easy work up, reusability of catalyst and high yields of the products. One new compound is reported too. Furthermore, the catalyst could be recycled after a simple work-up, and reused at least six times without substantial reduction in its catalytic activity.

关 键 词：Nano-titania-supported sulfonic acid Multicomponent reaction 2 4 6-Triarylpyridines Solvent free Heterogeneous nanocatalyst 

分 类 号：O643.36[理学—物理化学] TB383.1[理学—化学]