聚乙二醇功能化离子液体的制备及其在有机反应中的应用  

Preparation and Applications in Organic Reactions of Polyethylene Glycol Functionalized Ionic Liquids

作　　者：徐艺凇 张凤香[1] 厉嘉云[1] 白赢[1] 肖文军[1] 彭家建[1] 

机构地区：[1]杭州师范大学有机硅化学及材料技术教育部重点实验室,杭州311121

出　　处：《化学进展》2015年第10期1400-1412,共13页Progress in Chemistry

基　　金：国家自然科学基金项目(No.21303034;21203049);浙江省自然科学基金项目(No.LY14B030007)资助~~

摘　　要：聚乙二醇功能化离子液体作为一个新的研究方向受到了化学研究者关注,该类离子液体已经成功地应用于许多有机合成反应中,可以明显改善催化剂性能,并可在一定程度上解决传统催化剂使用中遇到的难分离、难回收再利用的问题。本文介绍了聚乙二醇功能化离子液体的发展历程、制备方法和其作为反应介质、溶剂或催化剂在有机合成反应中应用的最新研究成果,主要包括加成反应、缩合反应、还原反应、酯化反应、硝化反应、氧化反应、水解反应、Heck反应以及Suzuki-Miyaura反应等。The ionic liquids have been widely applied in the organic synthesis as a new reaction medium or catalysts, because of their special properties and excellent solubility with organic and inorganic compounds.Recently, polyethylene glycol-functionalized ionic liquids have attracted much attention from the researchers engaging in organic synthesis.The polyethylene glycol-functionalized ionic liquids merged the physical and chemical properties of ionic liquids and polyethylene glycol, so it can be used as better solvent or reaction medium than that of ionic liquids or polyethylene glycol respectively.On the other hand, the polyethylene glycol-functionalized ionic liquids could be easily modified with different functional groups, which can change the corresponding electronic properties by the modification of their structure.All this will contribute greatly to improve the catalytic performance in polyethylene glycol-functionalized ionic liquids involved organic reactions.The previous progress showed that there are several merits for the application of polyethylene glycol ionic liquids in organic synthesis, not only improved the catalytic activity and selectivity of reaction, but also simplified the work-up, and facilitated the separation and reuse of traditional catalyst.The paper summarizes the synthesis of various polyethylene glycol functionalized ionic liquids, and focused on the recent applications of polyethylene glycol functionalized ionic liquids as new reaction medium, or catalyst in organic reaction, including addition reaction, condensation reaction, reduction reaction, esterification, nitration reaction, oxidation reaction,hydrolysis reaction, Heck reaction, Suzuki-Miyaura coupling reaction, etc.

关 键 词：聚乙二醇离子液体 催化 有机合成 

分 类 号：O621.25[理学—有机化学]