超声支气管镜引导下经支气管针吸活检术在肺疾病中的早期诊断研究  

Ultrasonic bronchoscope guided transbronchial needle aspiration in the early diagnosis of pulmonary disease

作　　者：杨燕[1] 徐大敏[1] 王浩凌[1] 

机构地区：[1]四川省攀枝花市中心医院呼吸内科,617000

出　　处：《重庆医学》2015年第30期4219-4221,共3页Chongqing medicine

摘　　要：目的研究超声支气管镜引导下经支气管针吸活检术(EBUS-TBNA)在肺疾病的早期诊断中的高效性、安全性和并发症。方法选取2013年5月至2014年5月胸部CT提示胸内包块或纵隔淋巴结肿大的28例患者行EBUS-TBNA,穿刺标本行病理学检查。结果 28例患者中23例行EBUS-TBNA检查,EBUS-TBNA诊断出肺癌患者10例,转移性肿瘤4例,淋巴瘤3例,结核病3例,结节病2例,炎性患者1例。EBUS-TBNA诊断恶性肿瘤率高达74.0%,比预期诊断率明显升高(53.2%,P<0.01)。EBUS-TBNA诊断准确率:肺癌91.0%;淋巴瘤100.0%;转移性肿瘤75.0%;结核75.0%,结节病50.0%,炎性病变100.0%。所有行EBUS-TBNA检查患者,仅有2例出现轻度缺氧,1例出现出血症状。结论 EBUS-TBNA针对早期诊断呼吸疾病特别是纵隔肿块,是一种高效、微创、安全的检查手段。Objective To research high efficiency ,safety and complications of transbronchial needle aspiration biopsy under the guidance of ultrasound bronchoscope （EBUS‐TBNA ） in the early stage diagnosis of pulmonary disease .Methods Totally 28 patients showed intrathoracic mass or mediastinal lymph nodes by chest CT treated from May 2013 to May 2014 underwent EBUS‐TBNA ,and conducted biopsy for pathological examination .Results Among all the 28 patients ,23 patients underwent EBUS‐ TB‐NA ,10 patients were diagnosed as lung cancer ,4 patients had metastatic tumors ,3 patients were diagnosed lymphoma ,3 people were tuberculosis ,2 people were sarcoidosis ,1 patients with inflammatory .The EBUS‐TBNA diagnosis rate of malignant tumor was 74 .0% ,and the diagnosis rate was significantly higher than expectation （53 .2% ,P〈0 .01） .The accuracy of EBUS‐TBNA diagno‐sis was as follow ：91 .0% for lung cancer ,100 .0% for lymphoma ,75 .0% for metastatic tumor;75 .0% for tuberculosis ,50 .0% for sarcoidosis ,and 100 .0% for inflammatory lesions .Among all EBUS‐TBNA patients ,only two patients had mild hypoxia and one patient had bleeding .Conclusion EBUS‐TBNA was an effective ,minimally invasive ,safe means of inspection for the early diagnosis of respiratory diseases ,especially of mediastinal mass .

关 键 词：支气管内超声检查 超声支气管镜引导下的经支气管针吸活检术 胸内肿块 纵隔淋巴结 

分 类 号：R563[医药卫生—呼吸系统]