临床分离的产吲哚金黄杆菌耐药谱分析  

Analyze the drug-resistant spectrum of Chryseobacterium indologenes isolated from clinical

作　　者：解春宝[1] 罗天华[2] 罗江蓉[3] 喻华[1] 传良敏[1] 黄文芳[1] 

机构地区：[1]四川省医学科学院.四川省人民医院检验科,四川成都610072 [2]成都医学院检验医学院 [3]四川省医学科学院.四川省人民医院急诊科

出　　处：《中国实验诊断学》2015年第10期1725-1727,共3页Chinese Journal of Laboratory Diagnosis

摘　　要：目的分析本院临床分离的产吲哚金黄杆菌的药物敏感情况,指导临床合理用药。方法收集本院2012年1月-2013年12月期间临床分离的产吲哚金黄杆菌,采用法国生物梅里埃公司的全自动微生物分析仪VITEK-2进行菌株鉴定,以及VITEK-2配套药敏试验复合板进行药敏检测,分析其耐药谱。结果共收集了24株产吲哚金黄杆菌,且均呈现多重耐药谱。对碳青霉烯类抗生素亚胺培南的耐药率为95.8%。对头孢菌素类抗生素的耐药率很高,特别是对头孢唑林和头孢替坦的耐药率均为100%。对氨曲南的耐药率为100%,对磺胺类复方新诺明耐药率最低,为16.7%。结论本院分离的产吲哚金黄杆菌呈现多重耐药谱,对复方新诺明的敏感性最高。Objective To analyze the drug-resistant spectrum of Chryseobacterium indologenes isolated from clinical for rational using of antibiotics.Methods Chryseobacterium indologenes strains were isolated from our hospital.All the strains were identified by VITEK-2automatic bacterial identification system.Minimum inhibitory concentration of Chryseobacterium indologenes were determined using the VITEK-2composite panels for analyzing the drug-resistant spectrum.Results Twenty-four strains of Chryseobacterium indologenes were isolated and appeared multi-drug resistant spectrum in the study.The rate of isolated Chryseobacterium indologenes resistant to carbapenems was 95.8%.The rate of 24 strains resistant to cephalosporin antibiotics was very high.The drug-resistant rates of cefazolin and cefotetan were 100%.All the strains were resistance to aztreonam.The drug-resistant rates of compound sulfamethoxazole was the lowest（16.7%）.Conclusion In our hospital,Chryseobacterium indologenes present multi-drug resistant spectrum,the compound sulfamethoxazole has the highest sensitivity.

关 键 词：产吲哚金黄杆菌 耐药谱 多重耐药 

分 类 号：R446.5[医药卫生—诊断学]