空泡蝶鞍的 MRI 研究  

MRI study of empty sella

作　　者：宫少勇[1] 赵初青[1] 王文涛[1] 裘晟[1] 陈向飞[1] 汪凯[1] 刘文倩[1] 姚晓群[1] 杨广夫[1] 

机构地区：[1]西安交通大学附属高新医院影像科,陕西 西安710075

出　　处：《实用放射学杂志》2015年第10期1584-1588,共5页Journal of Practical Radiology

摘　　要：目的：研究空泡蝶鞍（ES）的 MRI 表现。方法收集在本院做头颅 MRI 检查32128例中诊断 ES 1280例,其中男436例,女844例,年龄11~90岁。全部病例使用 Philips Achieva 1.5T 双梯度磁共振机,使用头颅6通道相控阵线圈,做矢状位 T1 WI,横切位 T1 WI、T2 WI、T2 WI-FLAIR、DWI,冠状位 T1 WI、T2 WI 检查。结果ES 的发病率为3.98%（1280/32128例）,其中男性发病率2.61%（436/16691例）,女性发病率5.46%（844/15437例）,男女间发病率χ2=17.24,P =0.001,按照11~20岁,21~30岁,31~40岁,41~50岁,51~60岁,61~70岁,71~80岁,81~90岁分组,各组合计发病率为0.11%~5.20%,经统计学处理,各组合计例数、男性例数、女性例数发病率差异分别为χ2=55117.051,P =0.000；χ2=26294.920,P =0.000；χ2=21499.18,P =0.000。1280例中垂体腺矢状位高度均≤2.0 mm,合并蝶鞍扩大及垂体柄移位者792例（61.87%）,其中男255/436例（58.48%）,女537/844例（63.62%）,χ2=3.21,P =0.073。部分病例合并其他颅脑疾病。结论ES 是垂体腺的常见疾病,女性多见,随年龄增长发病率增高,两性间伴有蝶鞍扩大者无统计学差异。垂体腺高度≤2.0 mm 是诊断 ES 最重要的征象。Objective To study MRI findings of empty sella.Methods 1 280 cases of empty sella were collected from 32 128 cases of brain MRI scam in our hospital.There were 436 cases of male and 844 cases of female,with the age ranging 1 1-90 years.Philips Achieva 1.5T dual-gradent MR system with 6-phased array brain coil was used to MR scan.Saggital T1 WI and transverse T1 WI,T2 WI, T2 WI-FLAIR,DWI,and coronal T1 WI,T2 WI images were obtained in all patients.Results The incidence of empty sella was 3.98%（1 280/32 128 cases）,in which the incidence in male was 2.61% （436/16 691 cases）and in female 5.46% （844/15 437 cases）（χ2 =17.24,P =0.001）.The cases were divided into subgroups according to 1 1-20,21-30,31-40,41-50,5 1-60,61-70,71-80,81-90 years, the total incidence of subgroups were 0.1 1%-5.20%.The difference of incidence for total subgroups,male subgroups and female subgroups wereχ2 =55 1 1 7.05 1,P =0.000;χ2 =26 294.920,P =0.000;χ2 =21 499.180,P =0.000 respectively through the Chi test.The heigth of the pituitary in saggital position was ≤2.0 mm for all 1 280 patients,in which the enlargement of the sella and the dislocation of the pituitary handle were showed in 792 cases（61.87%）,which were showed in male group 255/436 cases（58.48%）, and in female 537/844cases（63.62%）（χ2 =3.21,P =0.073）.Other brain lesions were found in a lot of cases.Conclusion Empty sella is a comman disease of the pituitary grand,which is sean in the female patient and the aging peoples prodominently.Therse is no difference in accompaning with sella enlangement for both sex patients.The heigth of the pituitary grand （≤2.0 mm）is an important finding for diagnosis of empty sella.

关 键 词：蝶鞍 空泡蝶鞍 垂体腺 磁共振成像 

分 类 号：R584[医药卫生—内分泌] R445.2[医药卫生—内科学]