残端牵张并增强缝合修复兔急性前交叉韧带完全损伤的实验研究  

The research about remnant tension and augmented suture in acute complete rupture of anterior cruciate ligament in rabbits

作　　者：邓小文[1] 赵其纯[1] 尚希福[1] 李久源 吴星[1] 李丹[1] 王毅[1] 

机构地区：[1]安徽医科大学附属省立医院骨科,合肥230001

出　　处：《安徽医科大学学报》2015年第11期1683-1686,共4页Acta Universitatis Medicinalis Anhui

基　　金：安徽省科技厅重点科研项目(编号:11070403044)

摘　　要：取27只健康成年雌性新西兰大白兔于近前交叉韧带股骨止点处完全离断建立双侧急性前交叉韧带完全损伤模型,随机选择一侧膝关节采用自体半腱肌腱增强缝合残端并牵张技术修复前交叉韧带(L组),对侧行常规前交叉韧带重建(R组)。结果显示:术后第3、6、10周,L组移植物在组织学表现如腱骨界面愈合、细胞增殖、血管再生等方面上均优于R组;R组骨-移植物-骨复合体(骨-移植物-残端复合体)的最大载负荷要稍强于L组(P<0.05)。Acute complete ACL femoral rupture model of both two knee joints were created in all 27 rabbits. The ACL of one knee were repaired by remnant tension and augmented suture with semitendinosus tendon autografts（ L group）,and the contralateral one were subjected to anterior cruciate ligament reconstruction（ ACLR） with semitendinosus tendon autografts（ R group）,The group L presented enhanced tendon-bone healing,cellular proliferation and revascularization at 3th,6th,10 th postoprative week compared to the group R; the average maximum load of the group R was better than that of the group L（ P〈0. 05）.

关 键 词：前交叉韧带 完全损伤 残端牵张并增强缝合 移植物-残端愈合 

分 类 号：R686.5[医药卫生—骨科学]