7300例不规则抗体筛查结果的回顾性分析  

Retrospective analysis of 7300 cases of irregular antibody screening test results

作　　者：许桂平[1] 康琼华[1] 李晶晶[1] 高琦[1] 刘志东[1] 何海锋[1] 侯益军 张罗川 张娟[1] 

机构地区：[1]重庆医科大学附属第二医院输血科,400010

出　　处：《检验医学与临床》2015年第20期2984-2985,共2页Laboratory Medicine and Clinic

基　　金：国家自然科学基金资助项目(81101318)

摘　　要：目的回顾性分析某院近年不规则抗体筛查及鉴定结果,讨论不规则抗体筛查在临床输血中的意义。方法统计该院2013年3月至2014年3月需交叉配血患者的不规则抗体筛查结果,对初筛阳性的标本进一步用10组谱细胞进行抗体鉴定,统计不规则抗体的阳性结果。结果在7 300例患者中,不规则抗体阳性者有38例,阳性率为0.5%,其中抗-E阳性21例,抗-Lea阳性10例,抗-Fyb、抗-E联合抗-c阳性者各2例,抗-D、抗-c、抗-Jka、抗-M、抗-E联合抗-Fyb阳性者各1例。结论输血前进行不规则抗体筛查,有利于保证输血安全。Objective To retrospectively analyze the results of irregular antibody screening and identification in recent years,and to discuss the effects of irregular antibody screening in clinic transfusion.Methods The results of irregular antibody screening from March 2013 to March 2014 were collected and analyzed.The specimens containing irregular antibody were further identified by 10 panel cells.And the positive rates of irregular antibody were calculated.Results There were 38 cases of patients containing irregular antibodies among the 7 300 cases of patients,and the positive rate was 0.5%,of which 21 cases contained anti-E antibody,10 cases contained anti-Lea antibody,2cases contained anti-Fyb antibody,2cases contained both anti-E and anti-c antibody,1cases contained both anti-E and anti-Fyb antibody,and anti-D,anti-c,anti-Jka,anti-M antibody was respectively found in 1case.Conclusion Pretransfusion irregular antibody screening could ensure the safety of blood transfusion.

关 键 词：不规则抗体 筛查 输血安全 回顾性分析 

分 类 号：R457.1[医药卫生—治疗学]