高密度脂蛋白生物学功能及运动调节的研究与进展  

Biological function and exercise regulation of high-density lipoprotein

作　　者：苏中军[1,2,3] 张肃[3] 姜军[3] 

机构地区：[1]上海体育学院运动健康学院,上海市200438 [2]国家体育总局体育科学研究所,北京市100062 [3]沈阳体育学院运动人体科学学院,辽宁省沈阳市110102

出　　处：《中国组织工程研究》2015年第37期6048-6054,共7页Chinese Journal of Tissue Engineering Research

基　　金：科技部支撑计划项目(2012BAK23B01);国家体育总局体育科学研究所基本业务费项目(14-27)~~

摘　　要：背景:高密度脂蛋白是指与脂代谢有关的高密度脂蛋白,但研究表明其功能不仅局限于脂代谢范畴;同时运动调节高密度脂蛋白的活性和数量,但最佳的运动方式有待于研究。目的:总结高密度脂蛋白的生物学功能及运动调节高密度脂蛋白研究进展,展望了高密度脂蛋白研究的可能方向,旨在为健身训练方案的制定提供理论支持,为后续研究提供参考;方法:以关键词"HDL and exercise,HDL and biological function"搜索Pub Med数据库,筛选到1990至2015年间文章98篇;按纳入、排除标准最后纳入文献44篇。结果与结论:高密度脂蛋白主要功能包括介导糖、蛋白质、脂肪代谢、抗炎、抗氧化及介导胰岛素分泌的功能,同时总结运动对高密度脂蛋白浓度,分子数及组份影响的研究。研究表明抗阻与耐力组合训练提高高密度脂蛋白浓度及功能效果最显著。BACKGROUND;High-density lipoprotein is related to lipid metabolism,but its function cannot be restricted to the scope of lipid metabolism.Simultaneously,exercise regulation has effects on the activity and amount of high-density lipoprotein,but the optimal movement pattern needs to be studied.OBJECTIVE;To offer the theoretical support for formulating fitness training and prospect the possible direction and reference in follow-up studying the biological function and exercise regulation of high-density lipoprotein.METHODS;Pub Med database was searched for relevant articles published from 1990 to 2015 using the keywords of ＂HDL and exercise,HDL and biological function＂ in English.Finally,44 articles were included in result analysis.RESULTS AND CONCLUSION;The biological functions of high-density lipoprotein mainly include high-density lipoprotein-mediated metabolism of glucose,protein and fat,anti-inflammation,antioxidation and insulin secretion,and at the same time,we summarize the effects of exercise on the concentration,numbers of molecular and components of high-density lipoprotein.The results indicate that the combination of resistance and endurance training is the best way for raising the concentration and functional effects of high-density lipoprotein.

关 键 词：组织构建 组织工程 抗氧化 抗炎 代谢 训练 糖 蛋白质 

分 类 号：R318[医药卫生—生物医学工程]