基于图像数据建立器官三维模型  

Three-dimensional models of organs based on image data

作　　者：张海峰[1] 史冠忠 朱洪智[1] 宋翠荣[1] 赵长义[2] 任国山[2] 

机构地区：[1]沧州医学高等专科学校,河北省沧州市061001 [2]河北医科大学解剖教研室,河北省石家庄市050000

出　　处：《中国组织工程研究》2015年第40期6547-6552,共6页Chinese Journal of Tissue Engineering Research

基　　金：沧州市科技支撑计划项目~~

摘　　要：背景:近年来,三维重建与生物力学的研究日益增多,利用计算机由建模软件基于图像数据建立器官三维模型,再经有限元分析软件进行力学分析。作者检索文献发现国内外学者对人体器官三维重建的原理不够清晰,过程描述比较简单,有的与事实不尽相符,不能很好地为相关研究起到指导作用。目的:阐述器官三维模型重建的原理、过程、结果以及进一步应用,为后续研究提供科学依据。方法:应用计算机在中国知网数据库中检索关于人体器官三维重建有代表性的文献,分析阐述器官三维模型重建的原理、过程、结果以及进一步应用。结果与结论:结合建立出的骨三维模型详细阐述了三维重建的原理、过程、以及应用,为后续生物力学的研究奠定了理论基础。随着组织工程技术的不断发展,学者们己开始多角度、多方面来研究骨损伤的发病机制,以便更好地预防和治疗。相关研究现仍处于基础阶段,尚需深入研究。BACKGROUND： Recently, studies on three-dimensional reconstruction and biomechanics became more and more. Three-dimensional models of organs were established by modeling software based on image data using computer. Mechanical analysis was conducted using finite element analysis software. After literature retrieval, we found that the principle of three-dimensional reconstruction of human organs is not clear, and the process description is relatively simple. Some is not accorded with the fact. Above studies cannot guide related research. OBJECTIVE： To explore the principle, process, results and further application of three-dimensional reconstruction models of organs, and to provide evidence for future studies. METHODS： We retrieved China National Knowledge Infrastructure for representative literatures about three-dimensional reconstruction of human organs using the computer, and analyzed the principle, process, results and further application of three-dimensional reconstruction models of organs. RESULTS AND CONCLUSION： In combination with established three-dimensional bone models, we explained the principle, process, and application of three-dimensional reconstruction in detail, and laid the theoretical foundation for subsequent biomechanical research. With continuous development of tissue engineering technology, scholars have begun to study the pathogenesis of bone injury from various angles and different aspects so as to better prevent and treat this disease. The related research is still in its primary stage, and still needs further investigations.

关 键 词：组织工程 组织构建实验模型 三维模型 重建 骨三维模型 人体器官 

分 类 号：R318[医药卫生—生物医学工程]