前列地尔治疗慢性肾衰竭患者的疗效及其机制研究  

Study on the Effect and Mechanism of Alprostadil in the Treatment of Patients With Chronic Renal Failure

作　　者：秦丽芬[1] 

机构地区：[1]辽宁省本溪县第一人民医院,117000

出　　处：《中国继续医学教育》2015年第28期112-113,共2页China Continuing Medical Education

摘　　要：目的研究前列地尔治疗慢性肾衰竭患者的疗效,并对其机制进行深入研究。方法选取我院2013年2月~2015年2月收治的慢性肾衰竭患者100例为研究对象,将其随机分为2组,对照组给予常规对症治疗,观察组给予前列地尔治疗,比较分析2组治疗效果。结果两组患者在各临床指标间的差异显著,有统计学意义（P〈0.05）。结论前列地尔治疗慢性肾衰竭患者的疗效显著,其机制与肾血流动力学、降低尿蛋白、改善血液流变学等有直接相关性。Objective To study the curative effect of alprostadil in the treatment of patients with chronic renal failure,and further study of its mechanism.Methods In our hospital in February 2013 to February 2015 were chronic renal failure patients 100 cases as the research object,randomly divided to two groups,the control group was given routine symptomatic treatment,the observation group given alprostadil treatment,therapeutic effects of the two groups were compared and analyzed.Results The difference between the two groups was statistically significant（P〈0.05）.Conclusion Alprostadil in the treatment of patients with chronic renal failure curative effect is distinct,and the mechanism of renalhemodynamics,reduce urinary protein,improve the blood rheology etc.has a direct correlation.

关 键 词：前列地尔 慢性肾衰竭 机制研究 

分 类 号：R692.5[医药卫生—泌尿科学]