海南省单中心2型糖尿病控制现状调查与分析  

Investigation and analysis on the control status of type 2 diabetes mellitus in single center of Hainan province

作　　者：刘海蔚[1] 高勇义[1] 陈道雄[1] 陈开宁[1] 全会标[1] 林璐[1] 方团育[1] 莫泽纬[1] 

机构地区：[1]海南省人民医院内分泌科,海南海口570311

出　　处：《海南医学》2015年第20期3098-3101,共4页Hainan Medical Journal

基　　金：2014年度海南省卫计委立项普通科研课题(编号:14A200068)

摘　　要：目的评价海南省单中心2型糖尿病(T2DM)的控制现况。方法以2012年1月至2014年1月我院确诊的2 422例T2DM患者作为研究对象,参照2010版《中国2型糖尿病防治指南》推荐标准评价其控制水平。结果 (1)平均糖化血红蛋白(Hb A1c)为(8.77±3.58)%,其中658例(27.17%)患者Hb A1c<7%;(2)将2 422例T2DM患者按照用药情况分成未治疗组(占11.77%),口服降糖药治疗组(占58.71%),口服降糖药联合胰岛素治疗组(占15.28%)和胰岛素治疗组(占14.24%),后面两组患者的平均Hb A1c明显高于前面两组的平均Hb A1c,差异有统计学意义(P<0.05),而前面两组的平均Hb A1c比较差异则无统计学意义(P>0.05),后两组的达标率明显低于未治疗组(P<0.05);(3)2 422例T2DM患者的高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)和甘油三脂(TG)水平分别为(3.696±1.735)mmol/L、(1.23±0.41)mmol/L和(2.169±1.23)mmol/L;T2DM合并血脂异常者占76.42%,但服用调脂药者仅占30.02%;(4)2 422例糖尿病患者的平均SBP/DBP分别为(135.73±16.76)/(79.32±10.32)mm Hg,高血压者978例(40.38%),而服用降压药者仅270例(27.61%),其中血压达标者627例,占25.89%;(5)2 422例T2DM患者体质指数(BMI)为(25.43±3.43)kg/m2,BMI<24 kg/m2者占35.30%;(6)血糖、血脂、血压和BMI均在正常范围内者仅占3.14%。结论海南省单中心T2DM患者血糖、血脂、血压和BMI各项指标的控制明显落后于2010版《中国2型糖尿病防治指南》的推荐标准,胰岛素治疗时机明显滞后。Objective To evaluate the control status of types 2 diabetes mellitus （T2DM） in single center of Hainan province. Methods The patients with T2DM in our hospital from June 2012 to January 2014 were collected as subjects. The level of control was evaluated according to Chinese T2DM Prevention Guidelines （2010 veision）. Results （1） The 2 422 patients with T2DM had an average HbA1c level of （8.77±3.58）%, and 658 （27.17%） patients had HbA1〈7%. （2） According to drug use, the 2 422 T2DM patients were divided into untreated group （accounting for 11.77%）, oral hypoglycemic drug treatment group （58.71%）, oral hypoglycemic agents and insulin treatment group （15.28%） and insulin treatment group （14.24%）. The average HbA1c levels of the latter two groups were significantly higher than those in the former two groups, （P〈0.05）, with no statistically significant difference between the former two groups （P〈0.05）, and the compliance rates of the latter two groups were significantly lower than that of untreated group （P〈0.05）. （3） The levels of high-density lipoprotein cholesterol （HDL-C）, low-density lipoprotein cholesterol （LDL-C） and triglyceride （TG） were （3.696 ± 1.735） mmol/L, （1.23 ± 0.41） mmol/L and （2.169 ± 1.23） mmol/L. T2DM with dyslipidemia accounted for 76.42%, and only 30.02%took lipid-lowering drugs. （4） For the 2 422 patients, the mean systolic blood pressure （SBP） was （135.73±16.76）/（79.32±10.32） mmHg, with 978 （40.38%） patients having hy-pertension and 270 （27.61%）patients taking antihypertension drugs, 627 （25.89%） of which achieve successful blood pressure control. （5） The average body mass index （BMI） of the patients was （25.43±3.43） kg/m2, and 35.30%patients had BMI〈24 kg/m2. （6） Totally 76 patients （3.14%） had their glucose, blood liqids, blood pressure, and BMI meeting the standard. Conclusion The control of blood glucose, blood pressure, blood liqids, and BMI of T2

关 键 词：2型糖尿病 血糖控制 糖化血红蛋白 胰岛素 

分 类 号：R587.1[医药卫生—内分泌]