中草药抗弓形虫作用机制的研究进展  

Advances in researches on mechanism of anti-Toxoplasma Chinese herbal medicine

作　　者：于朝云[1] 张保德[1] 宁俊雅 王圆圆[1] 苑文英[1] 

机构地区：[1]河北大学,保定071000

出　　处：《中国血吸虫病防治杂志》2015年第5期555-557,559,共4页Chinese Journal of Schistosomiasis Control

基　　金：河北省科技厅基金项目(112761122);河北省医学科学研究重点课题计划(ZL20140224);保定市科学技术研究与发展指导计划(13ZF086)

摘　　要：弓形虫是一种专性细胞内寄生的机会性致病原虫,可感染多种动物和人,严重危害畜牧业生产和人类健康。由于弓形虫生活史复杂,形态各异,致病机理繁杂,目前尚无特效治疗和预防药物。中药具有平衡阴阳和整体调节机体免疫力的特点,毒副作用小,已成为治疗弓形虫病安全有效药物的研究热点。为进一步探寻中药的抗弓形虫作用机理及治疗效果,本文对黄芩、桦褐孔菌多糖、甘草、南瓜子和槟榔等中草药或其提取物的抗弓形虫机制及疗效等相关研究进展进行了综述。Toxoplasma gondii is an opportunity cellular parasite,related to the infection of various animals and human beings and severely impairing agriculture and human health. Because of the complexity of T. gondii life cycle,its different biological characteristics,and multifarious pathogenesis,there are no specific treatment and preventive medicines at present. Chinese herbal medicine can balance＂yin-yang＂and regulate the immunity and its side-effect is slight. Now,it has been a hot topic of the research on effective and secure medicines in anti-toxoplasmosis. This paper summarizes and analyzes the curative effect and mechanism of anti-Toxoplasma Chinese herbal medicine,such as Scutellaria baicalensis,Inontus obliquus polysaccharide,Radix glycyrrhizae,pumpkin seeds,and Semen arecae.

关 键 词：弓形虫 中草药 治疗 作用机制 

分 类 号：R531.8[医药卫生—内科学]