Enhancement of photoacoustic tomography in the tissue with speed-of-sound variance using ultrasound computed tomography  

作　　者：程任翔 陶超 刘晓峻 

机构地区：[1]Key Laboratory of Modern Acoustics of Ministry of Education, Department of Physics, Nanjing University

出　　处：《Chinese Physics B》2015年第11期63-69,共7页中国物理B（英文版）

基　　金：supported by the National Basic Research Program of China(Grant No.2012CB921504);the National Natural Science Foundation of China(Grant Nos.11422439,11274167,and 11274171);the Specialized Research Fund for the Doctoral Program of Higher Education,China(Grant No.20120091110001)

摘　　要：The speed-of-sound variance will decrease the imaging quality of photoacoustic tomography in acoustically inhomo- geneous tissue. In this study, ultrasound computed tomography is combined with photoacoustic tomography to enhance the photoacoustic tomography in this situation. The speed-of-sound information is recovered by ultrasound computed to- mography. Then, an improved delay-and-sum method is used to reconstruct the image from the photoacoustic signals. The simulation results validate that the proposed method can obtain a better photoacoustic tomography than the conventional method when the speed-of-sound variance is increased. In addition, the influences of the speed-of-sound variance and the fan-angle on the image quality are quantitatively explored to optimize the image scheme. The proposed method has a good performance even when the speed-of-sound variance reaches 14.2%. Furthermore, an optimized fan angle is revealed, which can keep the good image quality with a low cost of hardware. This study has a potential value in extending the biomedical application of photoacoustic tomography.The speed-of-sound variance will decrease the imaging quality of photoacoustic tomography in acoustically inhomo- geneous tissue. In this study, ultrasound computed tomography is combined with photoacoustic tomography to enhance the photoacoustic tomography in this situation. The speed-of-sound information is recovered by ultrasound computed to- mography. Then, an improved delay-and-sum method is used to reconstruct the image from the photoacoustic signals. The simulation results validate that the proposed method can obtain a better photoacoustic tomography than the conventional method when the speed-of-sound variance is increased. In addition, the influences of the speed-of-sound variance and the fan-angle on the image quality are quantitatively explored to optimize the image scheme. The proposed method has a good performance even when the speed-of-sound variance reaches 14.2%. Furthermore, an optimized fan angle is revealed, which can keep the good image quality with a low cost of hardware. This study has a potential value in extending the biomedical application of photoacoustic tomography.

关 键 词：photoacoustic tomography speed of sound ultrasound computed tomography 

分 类 号：O426.9[理学—声学] TP391.41[理学—物理]